Gaziantep University, Faculty of Medicine, Department of Medical Microbiology, Gaziantep, Turkey.
Rev Inst Med Trop Sao Paulo. 2024 Jul 29;66:e46. doi: 10.1590/S1678-9946202466046. eCollection 2024.
Stenotrophomonas maltophilia was considered to be a low-virulence organism. But it has emerged as a prominent opportunistic pathogen in patients with certain risk factors. This study aimed to describe an outbreak experienced in our hospital with all dynamics while evaluating previous S. maltophilia outbreak reports. S. maltophilia isolates were obtained from a university hospital in Türkiye in a seven-months period. Antimicrobial resistance, type of infections, predisposing factors of infected patients, antibiotic therapy, outcome of infections, and outbreak source were investigated. Also, S. maltophilia outbreaks in the literature were reviewed. In the 12 months prior to the outbreak, prevalence rate of clinical samples including S. maltophilia was 7/1,000 patient per day, opposed to 113/1,000 patient per day during the outbreak. Although a large number of cases were observed in a short seven-month period, a source of contamination could not be detected. Stable mortality rates (or remaining close to the average) during outbreaks can be attributed to the careful attention paid by laboratory and clinic physicians during procedures. S. maltophilia has potential to spread outbreaks and infect patients in operating rooms and intensive care units during invasive procedures.
嗜麦芽寡养单胞菌被认为是一种低毒力的生物体。但它已成为某些危险因素患者中一种重要的机会致病菌。本研究旨在描述我们医院所经历的一次暴发，并评估之前的嗜麦芽寡养单胞菌暴发报告。在七个月的时间里，从土耳其的一家大学医院获得了嗜麦芽寡养单胞菌分离株。研究了抗菌药物耐药性、感染类型、感染患者的易患因素、抗生素治疗、感染结果和暴发源。还回顾了文献中的嗜麦芽寡养单胞菌暴发情况。在暴发前的 12 个月中，包括嗜麦芽寡养单胞菌在内的临床样本的流行率为每天每 1000 名患者 7 例，而在暴发期间则为每天每 1000 名患者 113 例。尽管在短短七个月内观察到了大量病例，但仍未发现污染源。暴发期间稳定的死亡率（或接近平均值）可归因于实验室和临床医生在操作过程中小心谨慎。嗜麦芽寡养单胞菌在进行有创操作时，有在手术室和重症监护病房传播暴发和感染患者的潜力。
