Harik Sami I, Al-Hinti Jomana T, Archer R Lee, Angtuaco Edgardo J C
Departments of Neurology (SIH, JTA-H, RLA) and Radiology (EJCA), University of Arkansas for Medical Sciences, Little Rock.
Neurol Clin Pract. 2013 Feb;3(1):4-7. doi: 10.1212/CPJ.0b013e318283fef6.
The relationship between head trauma and parkinsonism has been debated since James Parkinson's first description of the shaking palsy in the late 19th century. We observed in our outpatient clinic a young woman in whom hemiparkinsonism developed within 3 weeks of sustaining closed head trauma with loss of consciousness. The patient had a discrete unilateral midbrain hemorrhage on head MRI which involved the contralateral substantia nigra. The condition responded well to carbidopa/levodopa. This patient is a convincing example of posttraumatic midbrain hemorrhage causing parkinsonism.
自19世纪末詹姆斯·帕金森首次描述震颤麻痹以来，头部创伤与帕金森病之间的关系一直存在争议。我们在门诊观察到一名年轻女性，她在遭受闭合性头部创伤并失去意识后的3周内出现了偏侧帕金森病。患者头部磁共振成像（MRI）显示有一个离散的单侧中脑出血，累及对侧黑质。该病症对卡比多巴/左旋多巴反应良好。这名患者是创伤后中脑出血导致帕金森病的一个有说服力的例子。
