长链非编码RNA MALAT1通过吸附miR-133来促进缺血再灌注损伤心脏中NLRP3炎性小体的表达。 - Suppr

LncRNA MALAT1 sponges miR-133 to promote NLRP3 inflammasome expression in ischemia-reperfusion injured heart.

作者信息

Yu Si-Yang, Dong Bo, Tang Liang, Zhou Sheng-Hua

机构信息

Department of Cardiovascular Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China.

出版信息

Int J Cardiol. 2018 Mar 1;254:50. doi: 10.1016/j.ijcard.2017.10.071. Epub 2018 Jan 28.

DOI:10.1016/j.ijcard.2017.10.071

PMID:29407129

Abstract

摘要

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LncRNA MALAT1 sponges miR-133 to promote NLRP3 inflammasome expression in ischemia-reperfusion injured heart.长链非编码RNA MALAT1通过吸附miR-133来促进缺血再灌注损伤心脏中NLRP3炎性小体的表达。

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LncRNA MALAT1 sponges miR-203 to promote inflammation in myocardial ischemia-reperfusion injury.长链非编码RNA MALAT1通过吸附微小RNA-203促进心肌缺血再灌注损伤中的炎症反应。

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TXNIP mediates NLRP3 inflammasome activation in cardiac microvascular endothelial cells as a novel mechanism in myocardial ischemia/reperfusion injury.TXNIP作为心肌缺血/再灌注损伤的一种新机制，介导心脏微血管内皮细胞中NLRP3炎性小体的激活。

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[NOD-like receptor pyrin domain containing 3 inflammasome and myocardial ischemia-reperfusion injury].含NOD样受体吡啉结构域蛋白3炎性小体与心肌缺血再灌注损伤

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Pharmacological Inhibition of NLRP3 Inflammasome Attenuates Myocardial Ischemia/Reperfusion Injury by Activation of RISK and Mitochondrial Pathways.NLRP3炎性小体的药理学抑制通过激活RISK和线粒体途径减轻心肌缺血/再灌注损伤

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Statin protects the heart against ischemia-reperfusion injury via inhibition of the NLRP3 inflammasome.他汀类药物通过抑制NLRP3炎性小体保护心脏免受缺血再灌注损伤。

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shRNA interference of NLRP3 inflammasome alleviate ischemia reperfusion-induced myocardial damage through autophagy activation.NLRP3炎性小体的短发夹RNA干扰通过自噬激活减轻缺血再灌注诱导的心肌损伤。

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Naoxintong attenuates Ischaemia/reperfusion Injury through inhibiting NLRP3 inflammasome activation.脑心通通过抑制NLRP3炎性小体激活减轻缺血/再灌注损伤。

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LncRNA MALAT1 sponges miR-133 to promote NLRP3 inflammasome expression in ischemia-reperfusion injured heart.

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