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前瞻性随访 20 年的边缘型人格障碍患者达到卓越康复时间的描述和预测。

Description and prediction of time-to-attainment of excellent recovery for borderline patients followed prospectively for 20 years.

机构信息

Laboratory for the Study of Adult Development, McLean Hospital, Belmont, MA, USA; Department of Psychiatry, Harvard Medical School, Boston, MA, USA.

Laboratory for the Study of Adult Development, McLean Hospital, Belmont, MA, USA; Department of Psychiatry, Harvard Medical School, Boston, MA, USA.

出版信息

Psychiatry Res. 2018 Apr;262:40-45. doi: 10.1016/j.psychres.2018.01.034. Epub 2018 Feb 20.

Abstract

One purpose of this study was to determine the cumulative rates of excellent recovery for borderline patients and axis II comparison subjects followed prospectively for 20 years. Another purpose was to find the best set of baseline predictors of excellent recovery for borderline patients. A total of 290 inpatients meeting rigorous criteria for borderline personality disorder and 72 axis II comparison subjects completed semistructured interviews and self-report measures during their index admission. Subjects were reassessed prospectively over 10 contiguous two-year waves of follow-up. Thirty-nine percent of borderline patients and 73% of personality-disordered comparison subjects met our operationalized definition of excellent recovery (concurrent remission of borderline or another primary personality disorder, good social and full-time vocational functioning, and absence of an axis I disorder associated decreased social and/or vocational functioning). Five variables formed our multivariate predictive model of excellent recovery for borderline patients: higher IQ, good childhood work history, good adult vocational record, lower trait neuroticism, and higher trait agreeableness. The results of this study suggest that complete recovery is difficult for borderline patients to achieve even over long periods of time. They also suggest that competence displayed in both childhood and adulthood is the best predictor of this important outcome.

摘要

这项研究的目的之一是确定前瞻性随访 20 年后,边缘型患者和轴 II 对照受试者的优秀恢复累积率。另一个目的是找到边缘型患者优秀恢复的最佳基线预测因子集。共有 290 名符合严格的边缘型人格障碍标准的住院患者和 72 名轴 II 对照受试者在其入院期间完成了半结构化访谈和自我报告测量。在连续的 10 个两年随访波中对受试者进行了前瞻性评估。39%的边缘型患者和 73%的人格障碍对照受试者符合我们优秀恢复的操作性定义(边缘型或另一种原发性人格障碍的同时缓解、良好的社会和全职职业功能,以及无与社会和/或职业功能下降相关的轴 I 障碍)。五个变量构成了我们边缘型患者优秀恢复的多变量预测模型:较高的智商、良好的儿童期工作史、良好的成人职业记录、较低的特质神经质和较高的特质宜人性。这项研究的结果表明,即使经过长时间,边缘型患者也很难实现完全恢复。它们还表明,在儿童期和成年期表现出的能力是这一重要结果的最佳预测因子。

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