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边缘型人格障碍:重新审视其作为神经发育障碍的分类。

Borderline personality: revisiting its classification as a neurodevelopmental disorder.

作者信息

Laurini Olivier, Strugarek Perrine, Rahioui Hassan

机构信息

Service des Troubles du Neuro-Développement chez l'Adulte (STNDA), Groupe Hospitalier Universitaire (GHU) Paris Psychiatrie et Neurosciences, Paris, France.

出版信息

Front Psychiatry. 2025 Jun 26;16:1587778. doi: 10.3389/fpsyt.2025.1587778. eCollection 2025.

DOI:10.3389/fpsyt.2025.1587778
PMID:40642419
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12241669/
Abstract

Although borderline personality disorder is classified as a personality disorder, many studies have developed arguments in favor of a neurodevelopmental origin. In order to methodologically advance this new conceptualization of the disorder, we have identified six criteria for inclusion in the diagnostic category of neurodevelopmental disorders and propose to examine the extent to which borderline disorder may meet these criteria, illustrating them with recent studies. Our review allows us to put forward the idea that this pathology could be considered as a late-onset neurodevelopmental disorder, present in childhood but fully manifesting in adolescence, a critical and rather explosive period of the developing brain. Such a perspective could help with early detection and treatment.

摘要

尽管边缘型人格障碍被归类为一种人格障碍,但许多研究已提出支持其具有神经发育起源的观点。为了在方法上推进对该障碍的这一新概念化,我们确定了纳入神经发育障碍诊断类别的六个标准,并提议考察边缘型障碍在多大程度上可能符合这些标准,并用近期研究加以说明。我们的综述使我们能够提出这样一种观点,即这种病理状况可被视为一种迟发性神经发育障碍,在儿童期就已存在,但在青春期才完全显现出来,而青春期是发育中大脑的一个关键且相当易变的时期。这样一种观点可能有助于早期发现和治疗。

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本文引用的文献

1
The course of borderline personality disorder from adolescence to early adulthood: A 5-year follow-up study.从青春期到成年早期的边缘型人格障碍病程:一项为期 5 年的随访研究。
Compr Psychiatry. 2024 Jul;132:152478. doi: 10.1016/j.comppsych.2024.152478. Epub 2024 Mar 21.
2
Twenty years of research on borderline personality disorder: a scientometric analysis of hotspots, bursts, and research trends.边缘型人格障碍二十年研究:热点、爆发点及研究趋势的科学计量分析
Front Psychiatry. 2024 Mar 1;15:1361535. doi: 10.3389/fpsyt.2024.1361535. eCollection 2024.
3
The role of thyroid function in borderline personality disorder and schizophrenia: a Mendelian Randomisation study.甲状腺功能在边缘型人格障碍和精神分裂症中的作用:一项孟德尔随机化研究。
Borderline Personal Disord Emot Dysregul. 2024 Feb 15;11(1):2. doi: 10.1186/s40479-024-00246-3.
4
Age dependent effects of early intervention in borderline personality disorder in adolescents.青少年边缘型人格障碍早期干预的年龄依赖性效应。
Psychol Med. 2024 Jul;54(9):2033-2041. doi: 10.1017/S0033291724000126. Epub 2024 Feb 12.
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The quest for a biological phenotype of adolescent non-suicidal self-injury: a machine-learning approach.探索青少年非自杀性自我伤害的生物学表型:一种机器学习方法。
Transl Psychiatry. 2024 Jan 25;14(1):56. doi: 10.1038/s41398-024-02776-4.
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Borderline personality disorder: a comprehensive review of diagnosis and clinical presentation, etiology, treatment, and current controversies.边缘型人格障碍:关于诊断与临床表现、病因、治疗及当前争议的全面综述
World Psychiatry. 2024 Feb;23(1):4-25. doi: 10.1002/wps.21156.
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Neurocognitive profile associated with borderline personality disorder: building specific indices of executive function.与边缘型人格障碍相关的神经认知特征:构建执行功能的特定指标。
Actas Esp Psiquiatr. 2023 Sep;51(5):220-228. Epub 2023 Sep 1.
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Therapeutic and Preventive Interventions in Adolescents with Borderline Personality Disorder: Recent Findings, Current Challenges, and Future Directions.边缘型人格障碍青少年的治疗与预防干预:最新发现、当前挑战及未来方向
J Clin Med. 2023 Oct 21;12(20):6668. doi: 10.3390/jcm12206668.
9
Borderline personality disorder and thyroid diseases: a Mendelian randomization study.边缘型人格障碍与甲状腺疾病:一项孟德尔随机化研究。
Front Endocrinol (Lausanne). 2023 Oct 3;14:1259520. doi: 10.3389/fendo.2023.1259520. eCollection 2023.
10
Oxytocin in the Treatment of Psychiatric Disorders.催产素在精神疾病治疗中的应用
Medeni Med J. 2023 Sep 28;38(3):218-231. doi: 10.4274/MMJ.galenos.2023.13707.