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泪液缺乏,小儿干眼症的罕见病因。

Alacrima, a rare cause of pediatric dry eye.

作者信息

Gupta Nidhi, Farooqui Javed Hussain, Agni Meghana, Kumar Abhishek, Sharma Mansi, Mathur Umang

机构信息

Dr. Shroff's Charity Eye Hospital, Daryaganj, New Delhi, India.

Dr. Shroff's Charity Eye Hospital, Daryaganj, New Delhi, India.

出版信息

J AAPOS. 2018 Jun;22(3):233-235. doi: 10.1016/j.jaapos.2017.11.003. Epub 2018 Feb 14.

DOI:10.1016/j.jaapos.2017.11.003
PMID:29408516
Abstract

We report the case of a 12-year-old boy who presented with a history of 4-5 years of severe bilateral photophobia, with exacerbation and increased ocular pain for 3-4 days. There were no systemic signs, and serology tests were negative; however, parents noted crying without tears since birth. Computerized tomography of the orbits revealed bilateral hypoplasia of lacrimal glands. A clinico-radiological correlation suggested a diagnosis of alacrima, a rare entity that should be considered in the differential diagnosis of severe pediatric dry eye, which is itself a commonly overlooked condition. In addition to artificial tears, permanent punctal occlusion with cautery provided symptomatic relief to the patient.

摘要

我们报告了一名12岁男孩的病例,他有4至5年的严重双侧畏光病史,在3至4天内病情加重且眼痛加剧。无全身症状,血清学检查为阴性;然而,父母注意到他自出生以来哭时无泪。眼眶计算机断层扫描显示双侧泪腺发育不全。临床与放射学相关性提示诊断为无泪症,这是一种罕见疾病,在小儿严重干眼症的鉴别诊断中应予以考虑,而小儿严重干眼症本身就是一种常被忽视的病症。除使用人工泪液外,烧灼法永久性泪点封闭为患者缓解了症状。

相似文献

1
Alacrima, a rare cause of pediatric dry eye.泪液缺乏,小儿干眼症的罕见病因。
J AAPOS. 2018 Jun;22(3):233-235. doi: 10.1016/j.jaapos.2017.11.003. Epub 2018 Feb 14.
2
Congenital alacrima.先天性无泪症。
Orbit. 2022 Apr;41(2):162-169. doi: 10.1080/01676830.2021.1974057. Epub 2021 Sep 5.
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Unilateral Congenital Lacrimal Gland Agenesis With Contralateral Lacrimal Gland Hypoplasia.单侧先天性泪腺缺如伴对侧泪腺发育不全
J Pediatr Ophthalmol Strabismus. 2015 Oct 15;52 Online:e52-4. doi: 10.3928/01913913-20151007-11.
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Isolated Bilateral Lacrimal Gland Agenesis.孤立性双侧泪腺发育不全
J Pediatr Ophthalmol Strabismus. 2016 Jul 30;53:e35-8. doi: 10.3928/01913913-20160719-01.
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Congenital alacrima in a patient with blepharophimosis syndrome.睑裂狭小综合征患者的先天性无泪症。
Ophthalmic Genet. 2009 Mar;30(1):37-9. doi: 10.1080/13816810802452176.
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Unilateral Alacrima as a Presenting Symptom of Nasopharyngeal Carcinoma.单侧无泪作为鼻咽癌的首发症状
Ophthalmic Plast Reconstr Surg. 2017 Mar/Apr;33(2):e41-e42. doi: 10.1097/IOP.0000000000000714.
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Congenital reduplication of the lacrimal punctum and canaliculus in a patient with dry eye.一名干眼症患者出现先天性泪小点和泪小管重复畸形。
Ophthalmic Surg Lasers Imaging. 2004 Mar-Apr;35(2):156-8.
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Lacrimal system abnormalities.泪器系统异常。
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New pathogenic variant in the FGF10 gene in the agenesis of lacrimal and salivary gland syndrome: Ophthalmological and genetic study.泪腺和唾液腺发育不全综合征中FGF10基因的新致病变异:眼科与遗传学研究
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Aqueous deficiency dry eye in post conjunctivitis cicatrization - Effect of deep thermal punctal cautery.结膜炎后瘢痕化导致的水样液缺乏性干眼症 - 深层热泪小点烧灼的效果。
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引用本文的文献

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Aqueous-deficient dry eye disease: Preferred practice pattern guidelines on clinical approach, diagnosis, and management.水液缺乏性干眼:临床方法、诊断和管理的首选实践模式指南。
Indian J Ophthalmol. 2023 Apr;71(4):1332-1347. doi: 10.4103/IJO.IJO_2808_22.
2
A comparative review of evaporative dry eye disease and meibomian gland dysfunction in dogs and humans.犬与人类蒸发过强型干眼症和睑板腺功能障碍的对比研究
Vet Ophthalmol. 2023 Apr;26 Suppl 1(Suppl 1):16-30. doi: 10.1111/vop.13066. Epub 2023 Feb 14.