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结膜炎后瘢痕化导致的水样液缺乏性干眼症 - 深层热泪小点烧灼的效果。

Aqueous deficiency dry eye in post conjunctivitis cicatrization - Effect of deep thermal punctal cautery.

机构信息

C J Shah Cornea Services, Dr. G Sitalakshmi Memorial Clinic for Ocular Surface Disorders, Sankara Nethralaya, Chennai, Tamil Nadu, India.

Department of Cornea and Refractive Surgery, Elite School of Optometry, Sankara Nethralaya, Medical Research Foundation, Chennai, Tamil Nadu, India.

出版信息

Indian J Ophthalmol. 2023 Apr;71(4):1630-1637. doi: 10.4103/IJO.IJO_2572_22.

Abstract

PURPOSE

To evaluate the effect of deep thermal punctal cautery in eyes with post-conjunctivitis cicatrization.

METHODS

This retrospective study consisted of patients who underwent deep thermal punctal cautery for post-conjunctivitis dry eye (PCDE). The diagnosis was based on a history suggestive of viral conjunctivitis in past followed by the onset of present clinical features of aqueous deficiency dry eye (ATD). All patients underwent a rheumatological evaluation to rule out underlying systemic collagen vascular disease as a cause for dry eye. The extent of cicatricial changes was noted. Best-corrected visual acuity (BCVA), Schirmer's test, and fluorescein staining score (FSS; total score of 9) were analyzed pre- and post-cautery.

RESULTS

Out of 65 patients (117 eyes), 42 were males. The mean age at presentation was 25.769 ± 12.03 years. Thirteen patients presented with unilateral dry eye. Pre-cautery BCVA (logarithm of the minimum angle of resolution [logMAR]) and Schirmer's test (mm) improved from 0.5251 ± 0.662 to 0.372 ± 0.595 (P value = 0.000, 95% confidence interval [CI]: 0.09-0.22), and 1.952 ± 2.763 to 4.929 ± 4.338 (P value = 0.000, 95% CI: -3.79--2.17); post-cautery, respectively. The pre-cautery FSS of 5.9 ± 2.82 reduced to 1.58 ± 2.38 (P value = 0.000, 95% CI: 3.46-5.17) post-cautery. The mean follow-up was 11.22 ± 13.32 months. No progression in cicatricial changes was noted in any eye during the follow-up. Re-canalization rate was 10.64%, and repeat cautery was performed with successful closure of puncta.

CONCLUSION

Symptoms and clinical signs of ATD in PCDE patients improve with punctal cautery.

摘要

目的

评估深层热泪点烧灼术治疗结膜瘢痕性干眼症(PCDE)的疗效。

方法

本回顾性研究纳入了因 PCDE 而接受深层热泪点烧灼术的患者。该诊断基于既往病毒性结膜炎病史,随后出现水样缺乏性干眼症(ATD)的当前临床特征。所有患者均接受了风湿评估,以排除潜在的全身性胶原血管疾病作为干眼症的病因。记录瘢痕形成的程度。分析术前和术后的最佳矫正视力(BCVA)、泪液分泌试验和荧光素染色评分(FSS;总分为 9 分)。

结果

65 例患者(117 只眼)中,男性 42 例。就诊时的平均年龄为 25.769 ± 12.03 岁。13 例患者为单侧干眼症。术前 BCVA(最小分辨角对数[logMAR])和泪液分泌试验(mm)从 0.5251 ± 0.662 提高到 0.372 ± 0.595(P 值=0.000,95%置信区间[CI]:0.09-0.22),1.952 ± 2.763 提高到 4.929 ± 4.338(P 值=0.000,95% CI:-3.79--2.17);术后分别。术前 5.9 ± 2.82 的 FSS 降低至 1.58 ± 2.38(P 值=0.000,95% CI:3.46-5.17)术后。平均随访时间为 11.22 ± 13.32 个月。在随访期间,没有观察到任何眼睛的瘢痕形成进展。再通率为 10.64%,并进行了重复烧灼以成功封闭泪点。

结论

深层热泪点烧灼术可改善 PCDE 患者的 ATD 症状和临床体征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4b1/10276737/4aa15f9334e4/IJO-71-1630-g001.jpg

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