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肾移植中免疫静止的机制与生物标志物

Mechanisms and biomarkers of immune quiescence in kidney transplantation.

作者信息

Chan-On Chitranon, Liberto Juliane M, Sarwal Minnie M

机构信息

Division of Nephrology, Faculty of Medicine, Department of Internal Medicine, Khon Kaen University, Khon Kaen, Thailand; Division of Transplant Surgery, Department of Surgery, University of California, San Francisco, San Francisco, CA, United States.

Division of Transplant Surgery, Department of Surgery, University of California, San Francisco, San Francisco, CA, United States.

出版信息

Hum Immunol. 2018 May;79(5):356-361. doi: 10.1016/j.humimm.2018.01.016. Epub 2018 Feb 19.

DOI:10.1016/j.humimm.2018.01.016
PMID:29408630
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10203980/
Abstract

This review discusses the current understanding of biomarkers of immune quiescence based on reviews of published literature in kidney transplant operational tolerance and mechanistic studies based on a better characterization of the stable, well-functioning renal allograft.

摘要

本综述基于已发表的关于肾移植手术耐受的文献综述以及基于对稳定、功能良好的肾移植受者更好特征描述的机制研究,探讨了目前对免疫静止生物标志物的理解。

相似文献

1
Mechanisms and biomarkers of immune quiescence in kidney transplantation.肾移植中免疫静止的机制与生物标志物
Hum Immunol. 2018 May;79(5):356-361. doi: 10.1016/j.humimm.2018.01.016. Epub 2018 Feb 19.
2
Regulatory dendritic cells for promotion of liver transplant operational tolerance: Rationale for a clinical trial and accompanying mechanistic studies.用于促进肝移植手术耐受的调节性树突状细胞:一项临床试验的理论依据及相关机制研究
Hum Immunol. 2018 May;79(5):314-321. doi: 10.1016/j.humimm.2017.10.017. Epub 2017 Oct 31.
3
T-regulatory cells in chronic rejection versus stable grafts.慢性排斥反应与稳定移植物中的调节性T细胞。
Exp Clin Transplant. 2015 Apr;13 Suppl 1:170-6.
4
The balance between memory and regulatory cell populations in kidney transplant recipients with operational tolerance.移植肾功能耐受受者中记忆性和调节性细胞群体之间的平衡。
Clin Exp Immunol. 2024 May 16;216(3):318-330. doi: 10.1093/cei/uxae018.
5
Infiltrating Foxp3(+) regulatory T cells from spontaneously tolerant kidney allografts demonstrate donor-specific tolerance.从自发耐受的肾移植中浸润的 Foxp3(+)调节性 T 细胞表现出供体特异性耐受。
Am J Transplant. 2013 Nov;13(11):2819-30. doi: 10.1111/ajt.12445. Epub 2013 Sep 18.
6
Immunological characteristics of renal transplant tolerance in humans.人类肾移植耐受的免疫学特征。
Mol Immunol. 2016 Sep;77:71-8. doi: 10.1016/j.molimm.2016.07.008. Epub 2016 Aug 1.
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Immunological biomarkers of tolerance in human kidney transplantation: An updated literature review.人类肾移植中耐受的免疫生物标志物:最新文献综述。
J Cell Physiol. 2019 May;234(5):5762-5774. doi: 10.1002/jcp.27480. Epub 2018 Oct 26.
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Contrib Nephrol. 2005;146:105-120. doi: 10.1159/000082071.
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CD4+CD25+ regulatory T cells-derived exosomes prolonged kidney allograft survival in a rat model.CD4+CD25+ 调节性 T 细胞衍生的外泌体延长大鼠肾移植模型的移植物存活时间。
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Recent Advances on Biomarkers of Early and Late Kidney Graft Dysfunction.早期和晚期肾移植功能障碍生物标志物的最新进展。
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引用本文的文献

1
Role of novel biomarkers in kidney transplantation.新型生物标志物在肾移植中的作用。
World J Transplant. 2020 Sep 18;10(9):230-255. doi: 10.5500/wjt.v10.i9.230.

本文引用的文献

1
Comparative Analyses of Signature Genes in Acute Rejection and Operational Tolerance.急性排斥反应与手术耐受中特征基因的比较分析
Immune Netw. 2017 Aug;17(4):237-249. doi: 10.4110/in.2017.17.4.237. Epub 2017 Aug 28.
2
DHRS9 Is a Stable Marker of Human Regulatory Macrophages.DHRS9是人类调节性巨噬细胞的稳定标志物。
Transplantation. 2017 Nov;101(11):2731-2738. doi: 10.1097/TP.0000000000001814.
3
Immune monitoring as prerequisite for transplantation tolerance trials.免疫监测作为移植耐受试验的前提条件。
Clin Exp Immunol. 2017 Aug;189(2):158-170. doi: 10.1111/cei.12988. Epub 2017 Jun 23.
4
Regulatory T cells: tolerance induction in solid organ transplantation.调节性T细胞:实体器官移植中的免疫耐受诱导
Clin Exp Immunol. 2017 Aug;189(2):197-210. doi: 10.1111/cei.12978. Epub 2017 May 25.
5
B Cell Receptor Genes Associated With Tolerance Identify a Cohort of Immunosuppressed Patients With Improved Renal Allograft Graft Function.B 细胞受体基因与耐受相关,可识别出一组免疫抑制患者,其肾移植移植物功能得到改善。
Am J Transplant. 2017 Oct;17(10):2627-2639. doi: 10.1111/ajt.14283. Epub 2017 May 2.
6
Mechanisms of Tolerance Induction by Hematopoietic Chimerism: The Immune Perspective.造血嵌合体诱导耐受的机制:免疫观点。
Stem Cells Transl Med. 2017 Mar;6(3):700-712. doi: 10.1002/sctm.16-0358. Epub 2017 Jan 3.
7
Tolerance in Kidney Transplantation: What Is on the B Side?肾移植中的耐受性:B 面是什么?
Mediators Inflamm. 2016;2016:8491956. doi: 10.1155/2016/8491956. Epub 2016 Nov 10.
8
Effect of tolerance versus chronic immunosuppression protocols on the quality of life of kidney transplant recipients.耐受性与慢性免疫抑制方案对肾移植受者生活质量的影响。
JCI Insight. 2016 Jun 2;1(8). doi: 10.1172/jci.insight.87019.
9
Transplantation Tolerance Induction: Cell Therapies and Their Mechanisms.移植耐受诱导:细胞疗法及其机制。
Front Immunol. 2016 Mar 7;7:87. doi: 10.3389/fimmu.2016.00087. eCollection 2016.
10
A pilot study of operational tolerance with a regulatory T-cell-based cell therapy in living donor liver transplantation.一项基于调节性 T 细胞的细胞治疗用于活体肝移植中获得免疫耐受的初步研究。
Hepatology. 2016 Aug;64(2):632-43. doi: 10.1002/hep.28459. Epub 2016 Mar 10.