Story L, Hutter J, Zhang T, Shennan A H, Rutherford M
Division of Women's Health, King's College London, St Thomas's Hospital, United Kingdom; Centre for the Developing Brain, King's College London, St Thomas's Hospital, United Kingdom.
Centre for the Developing Brain, King's College London, St Thomas's Hospital, United Kingdom.
Eur J Obstet Gynecol Reprod Biol. 2018 Mar;222:134-141. doi: 10.1016/j.ejogrb.2018.01.014. Epub 2018 Jan 31.
Preterm birth, defined as birth occurring prior to 37 weeks gestation is a common obstetric complication affecting 8% of pregnancies and is associated with significant morbidity and mortality. Infection/inflammation has been implicated in both the aetiology of preterm birth itself and associated neonatal pulmonary and neurological morbidity. Treatment options are currently limited to prolongation of the pregnancy using cervical cerclage, pessaries or progesterone or administration of drugs including steroids to promote lung maturity and neuroprotective agents such as magnesium sulphate, the timing of which are highly critical. Although delivery is expedited in cases of overt infection, decisions regarding timing and mode of delivery in subclinical infection are not clear-cut. This review aims to explore the use of magnetic resonance imaging (MRI) in the antenatal assessment of pregnancies at high risk of preterm birth and its potential to guide management decisions in the future.
早产定义为妊娠37周前出生，是一种常见的产科并发症，影响8%的妊娠，且与显著的发病率和死亡率相关。感染/炎症与早产本身的病因以及相关的新生儿肺部和神经疾病有关。目前的治疗选择仅限于使用宫颈环扎术、子宫托或孕酮延长妊娠，或使用包括类固醇在内的药物促进肺成熟以及使用硫酸镁等神经保护剂，而这些药物的使用时机至关重要。尽管在明显感染的情况下会加快分娩，但关于亚临床感染时分娩时机和方式的决策并不明确。本综述旨在探讨磁共振成像（MRI）在早产高危妊娠产前评估中的应用及其未来指导管理决策的潜力。
