Woldetensay Yitbarek Kidane, Belachew Tefera, Tesfaye Markos, Spielman Kathryn, Biesalski Hans Konrad, Kantelhardt Eva Johanna, Scherbaum Veronika
Institute of Biological Chemistry and Nutrition (140a), University of Hohenheim, Stuttgart, Germany.
Food Security Center, University of Hohenheim, Stuttgart, Germany.
PLoS One. 2018 Feb 6;13(2):e0191782. doi: 10.1371/journal.pone.0191782. eCollection 2018.
Semantic, technical, content, criterion and conceptual equivalence must be examined in order to validate a psychological rating scale in a new cultural setting. Few validation studies have been conducted in sub-Saharan Africa for scales seeking to detect depression in pregnant women. The aim of this study is to validate the 9-item Patient Health Questionnaire (PHQ-9) as a screening instrument for depression among Afaan Oromo speaking pregnant Ethiopian women.
A random sample of 246 pregnant women were recruited in Seka Chekorsa District, Ethiopia during their first, second or third trimester. One week later, 29 participants were selected to answer the questionnaire for a second time to evaluate test retest reliability. The Mini International Neuropsychiatric Interview (MINI-Plus) scale was used as a gold standard to evaluate validity. PHQ-9 was compared with MINI-Plus and sensitivity, specificity, accuracy, positive likelihood ratio, negative likelihood ratio and Receiver Operating Characteristic Curves (ROC) for PHQ-9 were calculated. Rasch analysis was also carried out using Winsteps version 3.81.0.
The reliability coefficient, Cronbach's alpha, for the PHQ-9 total score was 0.84. Both the agreement and consistency Intra-class Correlation coefficients (ICC) for the one-week test-retest reliability were 0.98. The cut-off point of a summed score of eight resulted in a sensitivity of 80.8% and a specificity of 79.5%. The calculated area under the curve (AUC) for the PHQ-9 score versus the MINI-Plus was excellent, 0.88 (SE = 0.04; CI = 0.81-0.95). The PHQ-9 meets the criteria established by Linacre for rating scale effectiveness.
The PHQ-9 proved to be a reliable and valid instrument that may be used to screen major depressive disorders among Afaan Oromo speaking Ethiopian pregnant women.
为了在新的文化背景下验证心理评定量表，必须检查语义、技术、内容、标准和概念的等效性。在撒哈拉以南非洲地区，针对旨在检测孕妇抑郁症的量表开展的验证研究很少。本研究的目的是验证9项患者健康问卷（PHQ-9）作为筛查埃塞俄比亚奥罗莫语裔孕妇抑郁症的工具。
在埃塞俄比亚的塞卡·切科尔萨区，随机抽取246名孕妇，她们处于孕早期、中期或晚期。一周后，选取29名参与者再次回答问卷，以评估重测信度。使用迷你国际神经精神访谈（MINI-Plus）量表作为评估效度的金标准。将PHQ-9与MINI-Plus进行比较，并计算PHQ-9的灵敏度、特异度、准确度、阳性似然比、阴性似然比和受试者工作特征曲线（ROC）。还使用Winsteps 3.81.0版进行了拉施分析。
PHQ-9总分的信度系数，即克朗巴哈系数为0.84。一周重测信度的组内相关系数（ICC）的一致性和稳定性均为0.98。总分8分的截断点对应的灵敏度为80.8%，特异度为79.5%。PHQ-9得分与MINI-Plus相比，计算出的曲线下面积（AUC）非常好，为0.88（SE = 0.04；CI = 0.81 - 0.95）。PHQ-9符合林acre制定的评定量表有效性标准。
PHQ-9被证明是一种可靠且有效的工具，可用于筛查埃塞俄比亚奥罗莫语裔孕妇中的重度抑郁症。
