Department of Psychiatry, Arsi University, College of Health Sciences, Asella, Ethiopia.
Department of Psychiatry, Jimma University, Jimma, Ethiopia.
BMJ Open. 2023 May 30;13(5):e070835. doi: 10.1136/bmjopen-2022-070835.
OBJECTIVE: It is crucial to use clinically validated instruments to detect and treat depression in people with epilepsy. Therefore, this study aimed to describe the psychometric properties of the Afaan Oromo version of the Hamilton Depression Rating Scale 17-item (HAMD-17) among these individuals in Ethiopia. DESIGN: A cross-sectional validation study. SETTING: A tertiary hospital, Southwest Ethiopia. PARTICIPANTS: A total of 133 people with epilepsy were included in this study using a consecutive sampling technique from 1 September 2020 to 30 September 2020. OUTCOME: The psychometric property of the HAMD-17. Criterion validity was assessed using the Mini-International Neuropsychiatric Interview (MINI). The internal consistency was determined using Cronbach's alpha. The receiver operating characteristic (ROC) analysis was used in determining the cut-off score, sensitivity, specificity and positive predictive value (PPV) and negative predictive value (NPV). The tools were translated into the local language (Afaan Oromo) and back into English and pretested before the data collection. RESULTS: The mean age of the participants was 31.7 years, SD±10.7. Eighty-six (64.7%), 55 (48.1%), 68 (51.1%) and 62 (46.6%) of them were male, unmarried, urban residents and completed primary school, respectively. The internal consistency of HAMD-17 was α=0.74. The Pearson's correlation coefficient for criterion validity was r=0.88. The ROC analysis showed 0.92 and 0.91 sensitivity and specificity of the HAMD-17, respectively. It also revealed α=0.96 NPV and α=0.87 PPV at a cut score of ≥9. The area under the ROC curve was 0.96. CONCLUSIONS: The Afaan Oromo version of the HAMD-17 was considered valid and reliable for assessing depression in people with epilepsy, and the tool is not difficult to understand. The diagnostic performance using the gold standard MINI showed a good discriminatory capacity of the instrument. It can be used by any health professional to screen depression in people with epilepsy.
目的：使用经过临床验证的工具来检测和治疗癫痫患者的抑郁症至关重要。因此，本研究旨在描述在埃塞俄比亚的这些人群中，使用奥罗莫语版汉密尔顿抑郁量表 17 项（HAMD-17）的心理测量特性。 设计：一项横断面验证研究。 地点：埃塞俄比亚西南部的一家三级医院。 参与者：本研究采用连续抽样技术，于 2020 年 9 月 1 日至 2020 年 9 月 30 日期间共纳入 133 名癫痫患者。 结局：HAMD-17 的心理测量特性。使用迷你国际神经精神访谈（MINI）评估效标效度。使用 Cronbach's alpha 确定内部一致性。使用受试者工作特征（ROC）分析确定截断值、灵敏度、特异性和阳性预测值（PPV）和阴性预测值（NPV）。这些工具被翻译成当地语言（奥罗莫语），然后再翻译成英语，并在数据收集前进行了预测试。 结果：参与者的平均年龄为 31.7 岁，标准差±10.7。其中 86（64.7%）、55（48.1%）、68（51.1%）和 62（46.6%）分别为男性、未婚、城镇居民和小学毕业。HAMD-17 的内部一致性为α=0.74。效标效度的皮尔逊相关系数为 r=0.88。ROC 分析显示 HAMD-17 的灵敏度和特异性分别为 0.92 和 0.91。ROC 分析还显示，截断值为≥9 时，HAMD-17 的阴性预测值为α=0.96，阳性预测值为α=0.87。ROC 曲线下面积为 0.96。 结论：奥罗莫语版 HAMD-17 被认为是评估癫痫患者抑郁的有效且可靠的工具，且该工具理解起来并不困难。使用金标准 MINI 进行的诊断性能表明该工具具有良好的区分能力。任何卫生专业人员都可以使用该工具来筛查癫痫患者的抑郁。
Zotero 插件