顶泌汗腺导管是否参与“汗疱疹”的发病机制？

Are acrosyringia involved in the pathogenesis of "dyshidrosis"?

作者信息

Kutzner H, Wurzel R M, Wolff H H

出版信息

Am J Dermatopathol. 1986 Apr;8(2):109-16. doi: 10.1097/00000372-198604000-00004.

DOI:10.1097/00000372-198604000-00004

Abstract

Investigations of dyshidrotic eruptions of various causes were done by conventional and electron microscopy. In all cases, the histological patterns were identical. The dyshidrotic vesicle is an intraepidermal, spongiotic lesion. The intraepidermal part of the eccrine sweat duct (acrosyringium) is not altered even by spongiosis. As the acrosyringium does not take part in formation of a dyshidrotic vesicle, the term "dyshidrosis" has to be regarded as a misnomer. Dyshidrosis is nothing but spongiotic dermatitis modified by the distinctive characteristics of palmar and plantar skin.

摘要

通过传统显微镜和电子显微镜对各种原因引起的汗疱疹进行了研究。在所有病例中，组织学模式都是相同的。汗疱疹性水疱是一种表皮内的海绵状病变。即使有海绵形成，小汗腺导管的表皮内部分（末端汗管）也不会改变。由于末端汗管不参与汗疱疹性水疱的形成，“汗疱疹”这个术语应被视为用词不当。汗疱疹只不过是由手掌和足底皮肤的独特特征所改变的海绵状皮炎。