Tsuji T, Sugai T, Suzuki S
J Invest Dermatol. 1975 Oct;65(4):388-93. doi: 10.1111/1523-1747.ep12607643.
Light and electron microscopic studies were performed utilizing serial sections in 10 patients with secondary milia to clarify the incidence of eccrine duct milia and to demonstrate the life history of the milia. Out of 69 milia after blistering taken from 8 patients, 52 were found to connect with the eccrine sweat duct (75.4%) while only 1 connected with the hair follicle (1.5%). In the control group, of 4 milia taken from 2 patients, 2 were found to connect with the eccrine sweat duct and 1 with the hair follicle. Various degrees of milium formation were observed ranging from incomplete and having either concave-shape, U-shape, capped U-shape, or O-shape. The eccrine duct milia in all types possess structures resembling the epidermal sweat duct unit. The epithelial cells constituting the recess or cyst differ from epidermal cells.
对10例继发性粟丘疹患者进行了光镜和电镜研究，利用连续切片来阐明小汗腺导管性粟丘疹的发生率，并展示粟丘疹的发生过程。在从8例患者水疱形成后取出的69个粟丘疹中，发现52个与小汗腺导管相连（75.4%），而仅有1个与毛囊相连（1.5%）。在对照组中，从2例患者取出的4个粟丘疹中，发现2个与小汗腺导管相连，1个与毛囊相连。观察到不同程度的粟丘疹形成，范围从不完全的，呈凹形、U形、帽状U形或O形。所有类型的小汗腺导管性粟丘疹均具有类似于表皮汗腺导管单位的结构。构成凹陷或囊肿的上皮细胞与表皮细胞不同。
