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理解癌症及其在泰医中的治疗:民族药理学-人类学研究。

Understanding cancer and its treatment in Thai traditional medicine: An ethnopharmacological-anthropological investigation.

机构信息

Center of Applied Thai Traditional Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wanglang Road, Bangkoknoi, Bangkok 10700, Thailand; Research Group Pharmacognosy and Phytotherapy, UCL School of Pharmacy, 29-39 Brunswick Square, London WC1N 1AX, UK.

Center of Applied Thai Traditional Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wanglang Road, Bangkoknoi, Bangkok 10700, Thailand.

出版信息

J Ethnopharmacol. 2018 Apr 24;216:259-273. doi: 10.1016/j.jep.2018.01.029. Epub 2018 Jan 31.

Abstract

ETHNOPHARMACOLOGICAL RELEVANCE

Thai traditional medicine (TTM) is widely practiced in Thailand and continues to gain importance in cancer management, but little is known about the TTM practitioners' emic concepts and practice.

AIM OF THE STUDY

With this study we firstly aim to document the practice of cancer treatment and prevention by TTM practitioners and, secondly, to evaluate how such traditional concepts and practices are correlated with biomedical ones. This in turn can form the basis for developing novel strategies for designing pharmacological experiments and longer term strategies to develop TTM practice.

METHODS

Semi-structured interviews with 33 TTM practitioners were performed in five provinces in different regions of Thailand. The following information were recorded; basic information of informants, descriptions of cancer (mareng in Thai), causes, diagnosis, treatment, and prevention. Plants used in the treatment and prevention of mareng were also collected.

RESULTS

Using an in depth ethnographic approach four representative case studies to assist in a better understanding of the characteristics of mareng, its diagnosis, treatment, and prevention are reported here. Five characteristics of mareng - waste accumulation (khong sia), chronic illnesses (krasai), inflammation (kan aksep), bad blood (luead) and lymph (namlueang), and the imbalance of four basic elements (dhātu si) - have been identified. Explanatory models of cancer in TTM were linked with biomedical concepts and relevant pharmacological actions. Traditional uses and available scientific evidence of medicinal plants mentioned in the case studies for the treatment or prevention of mareng are presented and discussed.

CONCLUSION

Here for the first time five main characteristics of cancer based on Thai traditional medical concepts are analysed. Our findings are relevant not only for the planning of clinical studies or pharmacological experiment in the search for novel compounds for cancer treatment and prevention, but also for the integration of Thai traditional medicine in cancer care.

摘要

民族药理学相关性

泰国传统医学(TTM)在泰国广泛应用,并在癌症管理中继续得到重视,但对于 TTM 从业者的本土概念和实践知之甚少。

研究目的

本研究首先旨在记录 TTM 从业者治疗和预防癌症的实践,其次评估这些传统概念和实践如何与生物医学概念相关联。这反过来又可以为设计药理学实验和制定长期发展 TTM 实践的策略提供基础。

方法

在泰国五个不同地区的省份对 33 名 TTM 从业者进行了半结构化访谈。记录的信息包括:受访者的基本信息、癌症(泰语中的 mareng)描述、病因、诊断、治疗和预防。还收集了用于治疗和预防 mareng 的植物。

结果

通过深入的民族志方法,我们报告了四个具有代表性的病例研究,以帮助更好地理解 mareng 的特征、其诊断、治疗和预防。我们确定了 mareng 的五个特征——废物堆积(khong sia)、慢性病(krasai)、炎症(kan aksep)、血液不良(luead)和淋巴(namlueang)以及四种基本元素(dhātu si)的失衡。TTM 中对癌症的解释模型与生物医学概念和相关的药理学作用相关联。我们提出并讨论了病例研究中提到的用于治疗或预防 mareng 的药用植物的传统用途和现有科学证据。

结论

我们首次分析了基于泰国传统医学概念的癌症的五个主要特征。我们的发现不仅与规划用于治疗和预防癌症的新型化合物的临床研究或药理学实验相关,而且与泰国传统医学在癌症护理中的整合相关。

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