Institute for Chemical Research, Kyoto University, Gokasho, Uji, Kyoto 611-0011, Japan.
Graduate School of Natural Sciences, Nagoya City University, Yamanohata 1, Mizuho-cho, Mizuho-ku, Nagoya, Aichi, 467-8501, Japan.
Angew Chem Int Ed Engl. 2018 Mar 19;57(13):3499-3503. doi: 10.1002/anie.201801222. Epub 2018 Feb 27.
The catalytic activation of small neutral molecules followed by the formation of C-C bonds is a highly important method to increase the complexity and/or value of simple starting materials. Reported is an isolable digermyne, a compound with a Ge≡Ge bond, which acts as a precatalyst for the cyclotrimerization of terminal arylacetylenes to afford the corresponding 1,2,4-triarylbenzenes with absolute regioselectivity. The results demonstrate that bespoke main-group-element compounds can catalytically activate and transform small neutral organic molecules and induce the formation of C-C bonds.
小分子的催化活化以及随后的 C-C 键形成，是增加简单起始原料的复杂性和/或价值的一种非常重要的方法。本文报道了一种可分离的二锗烷，它是一种具有 Ge≡Ge 键的化合物，可作为末端芳基乙炔环三聚反应的前催化剂，以绝对区域选择性得到相应的 1,2,4-三芳基苯。结果表明，定制的主族元素化合物可以催化活化和转化小的中性有机分子，并诱导 C-C 键的形成。
