Research and Technology Directorate , U.S. Army Edgewood Chemical Biological Center (ECBC) , Aberdeen Proving Ground , Maryland 21010 , United States.
Excet, Inc. 6225 Brandon Avenue, Suite 360 , Springfield , Virginia 22150 , United States.
ACS Appl Mater Interfaces. 2018 Mar 7;10(9):8359-8365. doi: 10.1021/acsami.7b19232. Epub 2018 Feb 21.
Paper spray mass spectrometry has been shown to successfully analyze chemical warfare agent (CWA) simulants. However, due to the volatility differences between the simulants and real G-series (i.e., sarin, soman) CWAs, analysis from an untreated paper substrate proved difficult. To extend the analytical lifetime of these G-agents, metal-organic frameworks (MOFs) were successfully integrated onto the paper spray substrates to increase adsorption and desorption. In this study, several MOFs and nanoparticles were tested to extend the analytical lifetimes of sarin, soman, and cyclosarin on paper spray substrates. It was found that the addition of either UiO-66 or HKUST-1 to the paper substrate increased the analytical lifetime of the G-agents from less than 5 min detectability to at least 50 min.
纸喷雾质谱已被证明可成功分析化学战剂（CWA）模拟物。然而，由于模拟物与实际 G 系列（即沙林、梭曼）CWA 之间的挥发性差异，未经处理的纸基质分析证明很困难。为了延长这些 G 型毒剂的分析寿命，成功地将金属-有机框架（MOFs）整合到纸喷雾基底上以增加吸附和脱附。在这项研究中，测试了几种 MOFs 和纳米粒子，以延长沙林、梭曼和环沙林在纸喷雾基底上的分析寿命。结果发现，将 UiO-66 或 HKUST-1 添加到纸基质中，可将 G 型毒剂的分析寿命从不到 5 分钟的检测时间延长至至少 50 分钟。
