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对2008年至2010年巴西塞阿拉州福塔雷萨市妊娠梅毒和先天性梅毒病例的分析。

Analysis of cases of gestational and congenital syphilis between 2008 and 2010 in Fortaleza, State of Ceará, Brazil.

作者信息

Cardoso Ana Rita Paulo, Araújo Maria Alix Leite, Cavalcante Maria do Socorro, Frota Mirna Albuquerque, Melo Simone Paes de

机构信息

Centro de Ciências da Saúde, Universidade de Fortaleza. Av. Washington Soares 1321, Edson Queiroz. 60811-341 Fortaleza CE Brasil.

Núcleo de Vigilância Epidemiológica do Hospital Geral Dr. César Cals, Secretaria de Saúde do Estado do Ceará. Fortaleza CE Brasil.

出版信息

Cien Saude Colet. 2018 Feb;23(2):563-574. doi: 10.1590/1413-81232018232.01772016.

Abstract

This study analyzes the reported cases of syphilis in pregnant women and the possible outcomes for fetuses and the newborn in Fortaleza, Ceará. It is a cross-sectional study that analyzed 175 reported cases of syphilis in pregnant women matched with the corresponding reports of congenital syphilis during the years 2008-2010. Descriptive statistics with absolute and relative frequencies, central tendency and dispersion measures, and the Pearson's chi-square test were used to analyze the statistical significance using the p-value <0.05. Sociodemographic variables of pregnant/postpartum women, the assistance provided to newborns and the outcome of cases were analyzed. The results showed the occurrence of syphilis in young women with more than 85% of inappropriate treatment, 62.9% of untreated sexual partners or lack of statistics and high percentages of non-realization of the recommended tests for congenital syphilis investigation in children. Among the fetuses, five were stillborn, one miscarried and there were three neonatal deaths. The lack of adequate treatment of pregnant women may be associated with morbidity and mortality of fetuses, maintaining this infection as a burden on the list of public health problems.

摘要

本研究分析了塞阿拉州福塔莱萨市孕妇梅毒报告病例以及胎儿和新生儿可能出现的结局。这是一项横断面研究,分析了2008年至2010年期间175例孕妇梅毒报告病例,并与相应的先天性梅毒报告进行匹配。使用绝对和相对频率、集中趋势和离散度测量的描述性统计方法,以及Pearson卡方检验,以p值<0.05来分析统计学意义。分析了孕妇/产后妇女的社会人口学变量、为新生儿提供的护理以及病例结局。结果显示,梅毒在年轻女性中出现,超过85%的治疗不当,62.9%的性伴侣未接受治疗或缺乏统计数据,并且在儿童先天性梅毒调查中,未进行推荐检测的比例很高。在胎儿中,有5例死产,1例流产,3例新生儿死亡。孕妇缺乏充分治疗可能与胎儿的发病率和死亡率相关,使这种感染仍然是公共卫生问题清单上的一个负担。

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