Iranzo Alex
Neurology Service, Multidisciplinary Sleep Unit, Hospital Clinic de Barcelona, C/ Villarroel 180, Barcelona 08036, Spain.
Sleep Med Clin. 2018 Mar;13(1):51-61. doi: 10.1016/j.jsmc.2017.09.005. Epub 2017 Nov 15.
Parasomnias and sleep-related movement disorders are important problems in older adults. Sleep paralysis is rare, but may occur in families. In a minority of patients with disorders of arousal, the episodes persist until the age of 70. Zolpidem and other medications may induce sleepwalking and sleep-related eating. Most patients with idiopathic rapid eye movement (REM) sleep behavior disorder eventually develop Parkinson's disease or dementia with Lewy bodies. Anti-IgLON5 disease includes abnormal behaviors in NREM and REM sleep. Restless legs syndrome prevalence increases with age. A severe form of periodic limb movements in sleep may mimic REM sleep behavior disorder.
异态睡眠和睡眠相关运动障碍是老年人的重要问题。睡眠瘫痪症较为罕见,但可能具有家族性。在少数觉醒障碍患者中,这些发作会持续到70岁。唑吡坦和其他药物可能诱发梦游和睡眠相关进食。大多数特发性快速眼动(REM)睡眠行为障碍患者最终会发展为帕金森病或路易体痴呆。抗IgLON5病包括非快速眼动(NREM)和快速眼动睡眠中的异常行为。不安腿综合征的患病率随年龄增长而增加。睡眠中严重形式的周期性肢体运动可能会模仿快速眼动睡眠行为障碍。