Department of Gastroenterology, School of Medicine, University of Sao Paulo, Av. Dr Arnaldo, 455, 2 andar, sala 2208-Cerqueira Cé sar, São Paulo, São Paulo CEP: 01246-903, Brazil.
Department of Gastroenterology, School of Medicine, University of Sao Paulo, Av. Dr Arnaldo, 455, 2 andar, sala 2208-Cerqueira Cé sar, São Paulo, São Paulo CEP: 01246-903, Brazil; Grupo Apoio Nutrição Enteral Parenteral-Human Nutrition, Maestro Cardim, 1236 - Paraíso, São Paulo 01323-001, Brazil.
Gastroenterol Clin North Am. 2018 Mar;47(1):231-242. doi: 10.1016/j.gtc.2017.09.009. Epub 2017 Dec 7.
Malnutrition is the most frequent nutritional disorder in patients with gastrointestinal cancer and is associated with cachexia syndrome, worsening of prognosis, and shortened survival rate. Early nutrition screening, assessment, and intervention are able to favorably modify the clinical evolution of affected patients. The adequate provision of nutritional requirements has been associated with improvement of immunologic status, and avoidance of further complications related to poor nutritional status, surgical treatment, and anticancer therapy. In malnourished patients, the supplementation of perioperative immunonutrition might contribute to fewer infectious and noninfectious complications, shorter length of hospitalization, and improved wound healing.
营养不良是胃肠道癌症患者最常见的营养障碍,与恶病质综合征、预后恶化和生存率缩短有关。早期营养筛查、评估和干预能够有利地改变受影响患者的临床转归。充足提供营养需求与改善免疫状态以及避免与营养不良、手术治疗和抗癌治疗相关的进一步并发症有关。在营养不良患者中,围手术期免疫营养的补充可能有助于减少感染和非感染性并发症、缩短住院时间和改善伤口愈合。