Eberl R, Bröll H
Agents Actions Suppl. 1979(5):139-48.
On the basis of theoretical considerations and the results of other authors we share the opinion of CEGLA that an early combined therapy of corticoids and D-penicillamine is the preferred therapy for pulmonary fibrosis. After subsidence of the exudative stages of pulmonary fibrosis the glucocorticoids should be, in our opinion, gradually reduced, so that a D-penicillamine therapy of a smaller dosage can also be efficient. However, a measurable therapeutical effect can only be objectively determined after a longer period of administration (approximately one year).
基于理论上的考量以及其他作者的研究结果，我们认同CEGLA的观点，即皮质类固醇与D-青霉胺的早期联合治疗是肺纤维化的首选治疗方法。我们认为，在肺纤维化渗出阶段消退后，应逐渐减少糖皮质激素的用量，这样较小剂量的D-青霉胺治疗也可能有效。然而，只有在较长时间（约一年）的给药后，才能客观地确定可测量的治疗效果。
