管状乳腺癌与浸润性导管癌（KROG 14-25）的失败模式比较。
Comparison of failure patterns between tubular breast carcinoma and invasive ductal carcinoma (KROG 14-25).
机构信息
Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
出版信息
Breast. 2018 Apr;38:165-170. doi: 10.1016/j.breast.2018.01.004. Epub 2018 Feb 3.
PURPOSE
Information on tubular carcinoma (TC) of breast is limited due to its rarity. A multi-institutional study was performed to investigate the prognosis and failure patterns of TC compared to invasive ductal carcinoma (IDC).
MATERIALS AND METHODS
We collected retrospective data on 205 patients with TC from eleven institutions. For each TC case, 3 cases with IDC were matched according to similar size, t-stage, and n-stage from the same institution. Patterns of failure, disease free survival (DFS) and overall survival (OS) were assessed and compared between the groups.
RESULTS
DFS at 5 years was 98.8% and 97.3% and OS at 5 years was 99.5% and 99.6% in TC and IDC, respectively. Among the patients with TC, 5 patients (2.4%) developed contralateral breast cancer, while 3 patients (0.5%) presented with contralateral breast cancer in patients with IDC.
CONCLUSIONS
The TC of breast presents an excellent prognosis, but the contralateral breast cancer tends to be more frequently observed compared to IDC in Korean women.
目的
由于管状癌（TC）罕见，因此有关其的信息有限。进行了一项多机构研究，以比较 TC 与浸润性导管癌（IDC）的预后和失败模式。
材料和方法
我们从 11 个机构收集了 205 例 TC 患者的回顾性数据。对于每例 TC 病例，均从同一机构中选择 3 例 IDC 病例，其大小、t 分期和 n 分期相似。评估并比较了两组之间的失败模式、无病生存率（DFS）和总生存率（OS）。
结果
TC 和 IDC 的 5 年 DFS 分别为 98.8%和 97.3%，5 年 OS 分别为 99.5%和 99.6%。在 TC 患者中，有 5 例（2.4%）发生对侧乳腺癌，而 IDC 患者中有 3 例（0.5%）发生对侧乳腺癌。
结论
韩国女性的 TC 乳腺癌预后良好，但与 IDC 相比，同侧乳腺癌的发生率更高。
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