Reilly Colin, Atkinson Patricia, Memon Ayesha, Jones Chloe, Dabydeen Lyvia, Das Krishna B, Gillberg Christopher, Neville Brian G R, Scott Rod C
Research Department, Young Epilepsy, Lingfield, Surrey RH7 6PW, UK; UCL Great Ormond Street Institute of Child Health (ICH), 30 Guilford Street, London WC1N 1EH, UK.
Child Development Centre, Crawley Hospital, West Green Drive, Crawley, RH11 7DH, West Sussex, UK.
Epilepsy Behav. 2018 Mar;80:177-183. doi: 10.1016/j.yebeh.2017.12.020. Epub 2018 Feb 3.
The objective was to provide population-based data on depression, anxiety, and stress in parents of young children with epilepsy and to compare findings with those of parents of developmental-, age-, and gender-matched children with nonepilepsy-related neurodisability (neurological and/or neurodevelopmental concerns). The parents (mothers and fathers) of 47 (89% ascertainment) young children (1-7years) with epilepsy in a defined geographical area of the UK completed the Depression Anxiety Stress Scales - Short Form (DASS-21), a screening measure for depression, anxiety, and stress. The responses of parents of children with epilepsy were compared with parents of developmental-, age-, and gender-matched children with nonepilepsy-related neurodisability (n=48). Factors associated with parental symptoms were analyzed using regression. In the group with epilepsy, 47 mothers and 39 fathers completed the DASS-21. Seventy-two percent of mothers scored in the at-risk range on at least one DASS-21 subscale (Fathers 49%). Mothers of children with epilepsy were significantly more likely to score in the at risk range than fathers on depression (55% vs. 33%), anxiety (47% vs. 26%), and stress (55% vs. 31%) subscales (all p<0.05). Mothers of children with epilepsy were also significantly more likely to score in the at-risk range than mothers of children with neurodisability on measures of depression (p=0.005) and stress (p=0.03). There was not a significant difference between fathers in both groups on any measures. In the group with epilepsy, increased child emotional-behavioral difficulties were associated with increased DASS-21 scores on multivariable analysis (p=0.04). Mothers of young children with epilepsy are at high risk for mental health difficulties, and all should be screened for such difficulties. There is a need to explore what parent and/or child focused interventions might be useful to reduce the mental health difficulties reported by mothers of young children with epilepsy.
目的是提供有关癫痫患儿父母抑郁、焦虑和压力的基于人群的数据，并将结果与发育、年龄和性别匹配的无癫痫相关神经残疾（神经和/或神经发育问题）儿童的父母进行比较。在英国一个特定地理区域内，47名（确定率89%）1至7岁癫痫幼儿的父母（母亲和父亲）完成了抑郁焦虑压力量表简表（DASS-21），这是一种用于筛查抑郁、焦虑和压力的工具。将癫痫患儿父母的回答与发育、年龄和性别匹配的无癫痫相关神经残疾儿童（n = 48）的父母进行比较。使用回归分析与父母症状相关的因素。在癫痫组中，47名母亲和39名父亲完成了DASS-21。72%的母亲在至少一个DASS-21子量表上得分处于风险范围（父亲为49%）。癫痫患儿的母亲在抑郁（55%对33%）、焦虑（47%对26%）和压力（55%对31%）子量表上得分处于风险范围的可能性显著高于父亲（所有p<0.05）。癫痫患儿的母亲在抑郁（p = 0.005）和压力（p = 0.03）测量上得分处于风险范围的可能性也显著高于神经残疾儿童的母亲。两组父亲在任何测量上均无显著差异。在癫痫组中，多变量分析显示儿童情绪行为困难增加与DASS-21得分增加相关（p = 0.04）。癫痫幼儿的母亲存在心理健康问题的高风险，所有母亲都应接受此类问题的筛查。有必要探索哪些以父母和/或儿童为重点的干预措施可能有助于减少癫痫幼儿母亲报告的心理健康问题。
