Cunningham M J, Zone J J, Petersen M J, Green J A
J Am Acad Dermatol. 1986 Jun;14(6):1039-41. doi: 10.1016/s0190-9622(86)70129-1.
A patient with classical hypostatic dermatitis-related autoeczematization was found to have an elevated ratio of helper to suppressor T lymphocytes and increased circulating activated T cells in the absence of detectable levels of circulating interferon. Despite the high levels of activated T cells, peripheral blood mononuclear leukocytes did not produce interferon spontaneously in culture. These findings suggest that autoeczematization is a form of cell-mediated autoimmunity and that activated T cells and interferon production may be unrelated in vivo.
一名患有典型坠积性皮炎相关自体湿疹化的患者，在未检测到循环干扰素水平的情况下，发现辅助性T淋巴细胞与抑制性T淋巴细胞的比例升高，循环活化T细胞增加。尽管活化T细胞水平很高，但外周血单个核白细胞在培养中不会自发产生干扰素。这些发现表明，自体湿疹化是细胞介导的自身免疫的一种形式，并且活化T细胞与干扰素产生在体内可能无关。
