眼部肿瘤学中的光动力疗法
Photodynamic Therapy in Ocular Oncology.
作者信息
Blasi Maria Antonietta, Pagliara Monica Maria, Lanza Angela, Sammarco Maria Grazia, Caputo Carmela Grazia, Grimaldi Gabriela, Scupola Andrea
机构信息
Department of Ophthalmology, Catholic University, 00168 Rome, Italy.
出版信息
Biomedicines. 2018 Feb 7;6(1):17. doi: 10.3390/biomedicines6010017.
Abstract
Although introduced for the treatment of maculopathies, photodynamic therapy (PDT) is now largely used in some eye cancers treatment. The selective tissue damage with PDT is achieved by sequestration of the photosensitizer in the target tissue and focal activation of the photosensitizer by low energy directed light. In this way, it is possible to achieve the destruction of the tumor tissue by safeguarding the surrounding healthy structures. Our study describes the clinical uses and efficacy of photodynamic therapy in ocular oncology.
摘要
尽管光动力疗法（PDT）最初是用于治疗黄斑病变的，但目前在一些眼部癌症的治疗中也得到了广泛应用。通过将光敏剂隔离在靶组织中，并利用低能量定向光对光敏剂进行局部激活，PDT实现了选择性组织损伤。通过这种方式，在保护周围健康结构的同时，有可能实现肿瘤组织的破坏。我们的研究描述了光动力疗法在眼部肿瘤学中的临床应用和疗效。
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