眼部肿瘤学中的光动力疗法

Mazloumi Mehdi, Dalvin Lauren A, Abtahi Seyed-Hossein, Yavari Negin, Yaghy Antonio, Mashayekhi Arman, Shields Jerry A, Shields Carol L

Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, USA.

Department of Ophthalmology, Mayo Clinic, Rochester, USA.

J Ophthalmic Vis Res. 2020 Oct 25;15(4):547-558. doi: 10.18502/jovr.v15i4.7793. eCollection 2020 Oct-Dec.

Over the past two decades, we have witnessed the increasing use of photodynamic therapy (PDT) in the field of ocular oncology. Based on a review of the literature and our own experience, we herein review the role of PDT for the management of intraocular tumors. The discussion includes two main topics. First, we discuss the application of PDT for benign tumors, including circumscribed choroidal hemangioma, choroidal osteoma, retinal astrocytoma, retinal capillary hemangioma (retinal hemangioblastoma), and retinal vasoproliferative tumor. Second, we assess the role of PDT for malignant tumors, including choroidal melanoma and choroidal metastasis.

在过去二十年中，我们目睹了光动力疗法（PDT）在眼部肿瘤学领域的使用日益增加。基于对文献的回顾以及我们自己的经验，我们在此回顾光动力疗法在眼内肿瘤治疗中的作用。讨论包括两个主要主题。第一，我们讨论光动力疗法在良性肿瘤中的应用，包括局限性脉络膜血管瘤、脉络膜骨瘤、视网膜星形细胞瘤、视网膜毛细血管瘤（视网膜成血管细胞瘤）和视网膜血管增生性肿瘤。第二，我们评估光动力疗法在恶性肿瘤中的作用，包括脉络膜黑色素瘤和脉络膜转移瘤。