Institute for Occupational Epidemiology and Risk Assessment (IERA), Evonik Industries AG, Rellinghauser Straße 1-11, 45128 Essen, Germany.
Int J Environ Res Public Health. 2018 Feb 6;15(2):276. doi: 10.3390/ijerph15020276.
With interest, I read the recent analysis by Tomaskova and co-workers (2017) about mortality from coal workers' pneumoconiosis (CWP). The research question remains unclear whether coal workers' pneumoconiosis (CWP) resulting from exposure to respirable coal dust containing crystalline silica accelerates the development of lung cancer or whether it is an intermediate stage in the pathway. I made several points of considerations with respect to (1) qualified data; (2) alternate measures for excessive risks; and (3) methodological flaws that should be avoided.
我饶有兴致地阅读了 Tomaskova 等人(2017 年)最近关于煤工尘肺(CWP)死亡率的分析。研究问题仍不清楚,暴露于含有结晶二氧化硅的可吸入煤尘导致的煤工尘肺(CWP)是否会加速肺癌的发展,或者它是否是该途径中的一个中间阶段。我就以下几个方面提出了一些考虑:(1)合格数据;(2)过度风险的替代措施;以及(3)应避免的方法学缺陷。