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在组织调理剂中加入表面预反应玻璃离子填料对白色念珠菌黏附的抑制作用。

Effect of incorporation of surface pre-reacted glass ionomer filler in tissue conditioner on the inhibition of Candida albicans adhesion.

作者信息

Takakusaki Kensuke, Fueki Kenji, Tsutsumi Chiaki, Tsutsumi Yusuke, Iwasaki Naohiko, Hanawa Takao, Takahashi Hidekazu, Takakuda Kazuo, Wakabayashi Noriyuki

机构信息

Removable Partial Prosthodontics, Tokyo Medical and Dental University (TMDU).

Department of Oral Medicine and Stomatology, Tsurumi University School of Dental Medicine.

出版信息

Dent Mater J. 2018 Jun 8;37(3):453-459. doi: 10.4012/dmj.2017-171. Epub 2018 Feb 8.

Abstract

We investigated the effects of incorporation of surface pre-reacted glass ionomer (S-PRG) filler in tissue conditioner (TC) on Candida albicans adhesion. We prepared specimens containing 0, 5, 10, or 20 wt% of S-PRG filler, and measured the amount of C. albicans on the surface using a colony forming unit (CFU) assay and scanning electron microscopic images. In addition, we measured the consistency, penetration depth, and surface roughness (Ra). CFU values for 10 and 20 wt% were significantly lower than that for the control (p<0.05). Hyphal density on the surface was greater in the control. The 10 and 20 wt% specimens showed significantly higher consistency and Ra, lower penetration depth ratio than control (p<0.05). These results suggest that incorporation of S-PRG filler may reduce C. albicans adhesion onto TC surface; however, the optimal amount of filler is dictated by the influence of filler incorporation on mechanical and surface characters of TC.

摘要

我们研究了在组织调理剂(TC)中加入表面预反应玻璃离子(S-PRG)填料对白色念珠菌黏附的影响。我们制备了含有0、5、10或20 wt% S-PRG填料的样本,并使用菌落形成单位(CFU)测定法和扫描电子显微镜图像测量了表面白色念珠菌的数量。此外,我们还测量了稠度、渗透深度和表面粗糙度(Ra)。10 wt%和20 wt%的CFU值显著低于对照组(p<0.05)。对照组表面的菌丝密度更大。10 wt%和20 wt%的样本显示出显著更高的稠度和Ra,渗透深度比低于对照组(p<0.05)。这些结果表明,加入S-PRG填料可能会减少白色念珠菌在TC表面的黏附;然而,填料的最佳用量取决于填料加入对TC机械和表面特性的影响。

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