Abualsaud Reem, Gad Mohammed M
Department of Substitutive Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Eur J Dent. 2023 Oct;17(4):1000-1011. doi: 10.1055/s-0042-1758788. Epub 2022 Dec 27.
This article aimed to review the ion and drug release, recharge abilities, and antimicrobial properties of drug/ion-releasing removable prostheses, and to assess their capability in preventing and inhibiting denture stomatitis as well preventing caries and reversing carious lesions. Data was collected from published scientific papers listed in PubMed database from January 1975 to December 2021. English full-text articles, involving clinical or studies, focusing on removable prostheses and are concerned with drug/ion release and rechargeability as a way to prevent or inhibit denture stomatitis or dental caries were included. The relevant articles reported that ion- or drug-modified polymethylmethacrylate acts as a reservoir for these ions and drugs and is capable of releasing significant amounts with sustained release effect. Recharging of modified resin resulted in greater sustainability of ion and drug release, thus improving the long-term effects of protection against demineralization and reducing the adhesion of and . Modifications of removable prostheses with rechargeable ions and drugs enhance remineralization, hinder demineralization, and reduce microbial adhesion in difficult-to-access areas. Selection of denture base for clinical use will consider its ability to act as an ion/drug reservoir that is capable of release and recharge.
本文旨在综述药物/离子释放型可摘义齿的离子和药物释放、再充电能力及抗菌性能，并评估其预防和抑制义齿性口炎以及预防龋齿和逆转龋损的能力。数据收集自1975年1月至2021年12月PubMed数据库中发表的科学论文。纳入了英文全文文章，这些文章涉及临床或研究，聚焦于可摘义齿，且关注药物/离子释放和再充电能力，以此作为预防或抑制义齿性口炎或龋齿的一种方式。相关文章报道，离子或药物改性的聚甲基丙烯酸甲酯可作为这些离子和药物的储存库，并能够以缓释效应释放大量物质。改性树脂的再充电导致离子和药物释放具有更高的可持续性，从而提高了防止脱矿的长期效果，并减少了（此处原文缺失相关内容）的黏附。用可再充电离子和药物对可摘义齿进行改性可增强再矿化、阻碍脱矿，并减少难以触及区域的微生物黏附。临床使用中义齿基托的选择将考虑其作为能够释放和再充电的离子/药物储存库的能力。
