Nicholson W J, Selikoff I J, Seidman H, Lilis R, Formby P
Ann N Y Acad Sci. 1979;330:11-21. doi: 10.1111/j.1749-6632.1979.tb18705.x.
Among a cohort of 544 men with at least 20 years of employment in chrysotile mining and milling at Thetford Mines, Canada, 16% of the deaths were from lung cancer and 15% from asbestosis. The excess over expected deaths from these causes account for 43 of 178 deaths in the group. The risk of death of asbestosis, at equal times fron onset of exposure, is very similar in miners and millers, factory workmen and insulators. The ratio of observed to expected deaths from lung cancer is similar in the miners and millers and factory workers, but higher in insulators. The risk of death of mesothelioma in miners and millers is decidedly less than the other two groups. The exact causes of the reduced risk in this category are not yet completely clarified.
在加拿大塞特福德矿从事温石棉开采和加工工作至少20年的544名男性队列中,16%的死亡是由肺癌导致的,15%是由石棉沉着病导致的。这些原因导致的死亡超出预期的部分占该组178例死亡中的43例。在相同暴露开始时间的情况下,矿工、工厂工人和绝缘工人患石棉沉着病的死亡风险非常相似。矿工、工厂工人患肺癌的观察死亡与预期死亡之比相似,但绝缘工人的这一比例更高。矿工和工厂工人患间皮瘤的死亡风险明显低于其他两组。这一类别中风险降低的确切原因尚未完全阐明。