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接触石棉会导致胃肠道癌症吗?

Does asbestos exposure cause gastrointestinal cancer?

作者信息

Levine D S

出版信息

Dig Dis Sci. 1985 Dec;30(12):1189-98. doi: 10.1007/BF01314055.

Abstract

The relationship between asbestos exposure and gastrointestinal malignancies is unlike the well-established correlation between occupational asbestos exposure and the subsequent development of pleuropulmonary neoplasms and mesotheliomas. Cohort studies on occupationally exposed workers suggest an association between asbestos and gastrointestinal cancer, but evaluation of dose-response, tissue analysis, animal experiment, and cell culture data yield inconsistent conclusions. No simplistic cause-effect relationship can be ascribed to asbestos at the present time, and the answer to the question, "Does asbestos exposure cause cancer?" must await the results of additional studies.

摘要

石棉暴露与胃肠道恶性肿瘤之间的关系,不同于职业性石棉暴露与随后发生的胸膜肺肿瘤和间皮瘤之间已明确的关联。针对职业暴露工人的队列研究表明石棉与胃肠道癌症之间存在关联,但对剂量反应、组织分析、动物实验及细胞培养数据的评估得出了不一致的结论。目前,无法将简单的因果关系归因于石棉,“石棉暴露会导致癌症吗?”这个问题的答案必须等待更多研究的结果。

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