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化工行业维修工人中的石棉病

Asbestos disease in maintenance workers of the chemical industry.

作者信息

Lilis R, Daum S, Anderson H, Sirota M, Andrews G, Selikoff I J

出版信息

Ann N Y Acad Sci. 1979;330:127-35. doi: 10.1111/j.1749-6632.1979.tb18713.x.

Abstract

In several large groups of workers employed in chemical plants, chest x-ray abnormalities (small irregular opacities and/or pleural changes) of the type known to be induced by asbestos were found in a proportion of those examined. A cross-sectional study of maintenance workers in a large chemical plant was undertaken to evaluate the prevalence of asbestosis; 185 workers were examined. Radiologic evidence of parenchymal interstitial fibrosis was found in 24% of those examined; in 10% of workers, parenchymal fibrosis was the only abnormality. Pleural fibrosis and/or calcification was found in the absence of parenchymal fibrosis in 14% of cases; in another 14% of workers, both parenchymal and pleural abnormalities were detected. The prevalence was significantly higher in those employed 20 or more years. Pleural abnormalities were more prevalent than were parenchymal changes. The increased risk of lung cancer and mesothelioma remains to be studied.

摘要

在几组受雇于化工厂的大量工人中,在一部分接受检查的工人身上发现了已知由石棉诱发的那种胸部X光异常(小的不规则阴影和/或胸膜改变)。对一家大型化工厂的维修工人进行了一项横断面研究,以评估石棉沉着病的患病率;对185名工人进行了检查。在24%的受检者中发现了实质性间质纤维化的放射学证据;在10%的工人中,实质性纤维化是唯一的异常。在14%的病例中,在没有实质性纤维化的情况下发现了胸膜纤维化和/或钙化;在另外14%的工人中,同时检测到了实质性和胸膜异常。在工作20年或更长时间的人群中,患病率显著更高。胸膜异常比实质性改变更普遍。肺癌和间皮瘤风险增加的情况仍有待研究。

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