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Targeting altered Nme heterooligomerization in disease?

作者信息

Abu-Taha Issam H, Vettel Christiane, Wieland Thomas

机构信息

Institute of Experimental and Clinical Pharmacology and Toxicology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; DZHK (German Center for Cardiovascular Research), Partner Site, Heidelberg-Mannheim, Germany.

出版信息

Oncotarget. 2017 Nov 27;9(2):1492-1493. doi: 10.18632/oncotarget.22716. eCollection 2018 Jan 5.

DOI:10.18632/oncotarget.22716
PMID:29416708
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5788576/
Abstract
摘要

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Hepatitis C Virus E1 protein promotes cell migration and invasion by modulating cellular metastasis suppressor Nm23-H1.丙型肝炎病毒E1蛋白通过调节细胞转移抑制因子Nm23-H1促进细胞迁移和侵袭。
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[Mutational analysis of nm23-H1 gene in human lung cancer by polymerase chain reaction-single strand conformation polymorphism].
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本文引用的文献

1
Nucleoside Diphosphate Kinase-C Suppresses cAMP Formation in Human Heart Failure.核苷二磷酸激酶 C 抑制人心力衰竭时 cAMP 的形成。
Circulation. 2017 Feb 28;135(9):881-897. doi: 10.1161/CIRCULATIONAHA.116.022852. Epub 2016 Dec 7.
2
Alterations in reversible protein histidine phosphorylation as intracellular signals in cardiovascular disease.可逆性蛋白质组氨酸磷酸化作为心血管疾病细胞内信号的改变
Front Pharmacol. 2015 Aug 21;6:173. doi: 10.3389/fphar.2015.00173. eCollection 2015.
3
Progress on Nme (NDP kinase/Nm23/Awd) gene family-related functions derived from animal model systems: studies on development, cardiovascular disease, and cancer metastasis exemplified.源自动物模型系统的Nme(NDP激酶/Nm23/Awd)基因家族相关功能研究进展:以发育、心血管疾病及癌症转移研究为例
Naunyn Schmiedebergs Arch Pharmacol. 2015 Feb;388(2):109-17. doi: 10.1007/s00210-014-1079-9. Epub 2015 Jan 15.
4
A critical evaluation of biochemical activities reported for the nucleoside diphosphate kinase/Nm23/Awd family proteins: opportunities and missteps in understanding their biological functions.对核苷二磷酸激酶/Nm23/Awd家族蛋白所报道的生化活性的批判性评估:理解其生物学功能过程中的机遇与失误
Naunyn Schmiedebergs Arch Pharmacol. 2011 Oct;384(4-5):331-9. doi: 10.1007/s00210-011-0651-9. Epub 2011 May 25.
5
Reversible histidine phosphorylation in mammalian cells: a teeter-totter formed by nucleoside diphosphate kinase and protein histidine phosphatase 1.哺乳动物细胞中的可逆组氨酸磷酸化:由核苷二磷酸激酶和蛋白质组氨酸磷酸酶1形成的跷跷板。
Methods Enzymol. 2010;471:379-402. doi: 10.1016/S0076-6879(10)71020-X. Epub 2010 Mar 1.
6
The interaction of nucleoside diphosphate kinase B with Gbetagamma dimers controls heterotrimeric G protein function.核苷二磷酸激酶B与Gβγ二聚体的相互作用控制异源三聚体G蛋白的功能。
Proc Natl Acad Sci U S A. 2009 Sep 22;106(38):16269-74. doi: 10.1073/pnas.0901679106. Epub 2009 Sep 4.
7
Inhibition of Nm23H2 gene product (NDPK-B) by angiostatin, polyphenols and nucleoside analogs.血管抑素、多酚和核苷类似物对Nm23H2基因产物(NDPK-B)的抑制作用。
Proc West Pharmacol Soc. 2008;51:30-4.
8
Quaternary structure of nucleoside diphosphate kinases.核苷二磷酸激酶的四级结构。
J Bioenerg Biomembr. 2000 Jun;32(3):227-36. doi: 10.1023/a:1005580828141.