Department of Pediatrics, University of Louisville, Weisskopf Center/UofL Autism Center, Louisville, KY, USA.
Department of Occupational Therapy Education, University of Kansas Medical Center, Kansas City, KS, USA.
J Autism Dev Disord. 2018 Jun;48(6):2139-2147. doi: 10.1007/s10803-018-3468-2.
Given the heterogeneity of autism spectrum disorder (ASD), research has investigated how sensory features elucidate subtypes that enhance our understanding of etiology and tailored treatment approaches. Previous studies, however, have not integrated core developmental behaviors with sensory features in investigations of subtypes in ASD. Therefore, we used latent profile analysis to examine subtypes in a preschool aged sample considering sensory processing patterns in combination with social-communication skill, motor performance, and adaptive behavior. Results showed four subtypes that differed by degree and quality of sensory features, age and differential presentation of developmental skills. Findings partially align with previous literature on sensory subtypes and extends our understanding of how sensory processing aligns with other developmental domains in young children with ASD.
鉴于自闭症谱系障碍（ASD）的异质性，研究已经探讨了如何通过感觉特征来阐明亚类，从而增进我们对病因和针对性治疗方法的理解。然而，以前的研究并没有将核心发展行为与 ASD 亚类研究中的感觉特征结合起来。因此，我们使用潜在剖面分析来研究学龄前样本的亚类，考虑到感觉处理模式与社会交流技能、运动表现和适应行为相结合。结果显示，有四个亚类在感觉特征的程度和质量、年龄以及发育技能的不同表现方面存在差异。研究结果部分与以前关于感觉亚类的文献一致，并扩展了我们对感觉处理如何与 ASD 幼儿其他发展领域相协调的理解。
