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大鼠条件性情绪反应的条件性抑制剂

Conditioned inhibitor of the conditioned emotional response in rats.

作者信息

Wesierska M, Zielinski K

出版信息

Physiol Bohemoslov. 1985;34 Suppl:177-81.

PMID:2941789
Abstract

Properties of a conditioned inhibitor (CI) were studied using the conditioned emotional response (CER) method. The classical defensive response (suppression of the on-going barpressing for food) was first established using 3 min of the white noise conditioned stimulus (CS) and foot shock unconditioned stimulus (US). Then the conditioned inhibitor, a 4 min house light offset, was introduced. During the last 3 min the CI was presented together with CS and not paired with the shock. The rapidly of CER training and also the efficacy of the CI training were both positively correlated with the CS intensity. The final effect of the CI + CS complex enhanced barpressing, whereas the CS alone suppressed it as before. The extinction of the CER resulted in the recovery of the regular barpressing rate during the CS and the CI + CS complex. Presentations of free shocks resulted in a temporary reinstatement of the suppressing effect of the CS and the enhancing effect of the CI + CS. The efficacy of inhibitory training depended on the alimentary motivation level.

摘要

使用条件性情绪反应(CER)方法研究了条件性抑制剂(CI)的特性。首先使用3分钟的白噪声条件刺激(CS)和足部电击非条件刺激(US)建立经典防御反应(抑制正在进行的食物按压杆行为)。然后引入条件性抑制剂,即4分钟的室内灯光熄灭。在最后3分钟内,CI与CS同时呈现且不与电击配对。CER训练的速度以及CI训练的效果均与CS强度呈正相关。CI + CS复合物的最终效果增强了按压杆行为,而单独的CS则如前一样抑制了该行为。CER的消退导致在CS和CI + CS复合物期间正常按压杆速率的恢复。给予自由电击导致CS的抑制作用和CI + CS的增强作用暂时恢复。抑制训练的效果取决于食物动机水平。

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1
Conditioned inhibitor of the conditioned emotional response in rats.大鼠条件性情绪反应的条件性抑制剂
Physiol Bohemoslov. 1985;34 Suppl:177-81.
2
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Acta Neurobiol Exp (Wars). 1980;40(6):945-63.
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