Urmancheva T G, Fufacheva A A, Capek K, Kunes J, Jelínek J
Physiol Bohemoslov. 1986;35(2):112-7.
The influence of experimental neurosis due to repeated conflict situations on blood pressure was studied in male monkeys. All animals developed hypertension demonstrable in the conscious state but which disappeared under pentobarbital anaesthesia. Both in conscious and anaesthetized animals, the pulse pressure was in-elevated. The hypertension was accompanied by increased plasma volume to interstitial volume ratio, due to a decrease of the interstitial fluid compartment. The plasma renin concentration was not raised. It is suggested that chronic increase in blood pressure might be responsible for the decrease in compliance of large arteries (as evidenced by increased pulse pressure). This form of hypertension does not depend on the activity of the renin-angiotensin system.
在雄性猴子身上研究了因反复冲突情境导致的实验性神经症对血压的影响。所有动物在清醒状态下均出现了可证实的高血压,但在戊巴比妥麻醉下消失。无论是清醒还是麻醉的动物,脉压均升高。高血压伴随着血浆量与组织间隙量比值的增加,这是由于组织间隙液腔室减少所致。血浆肾素浓度未升高。有人提出,血压的慢性升高可能是大动脉顺应性降低的原因(脉压升高证明了这一点)。这种形式的高血压不依赖于肾素 - 血管紧张素系统的活性。