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葡萄膜炎患者发生孔源性视网膜脱离的危险因素。

Risk Factors for Development of Rhegmatogenous Retinal Detachment in Patients with Uveitis.

机构信息

a Department of Ophthalmology, Faculty of Medicine , Chiang Mai University , Chiang Mai , Thailand.

b Department of Ophthalmology , Erasmus Medical Center , Rotterdam , The Netherlands.

出版信息

Ocul Immunol Inflamm. 2019;27(4):681-685. doi: 10.1080/09273948.2018.1424343. Epub 2018 Feb 8.

DOI:10.1080/09273948.2018.1424343
PMID:29420113
Abstract

: To describe risk factors for development of rhegmatogenous retinal detachment (RRD) in patients with uveitis. : We performed a retrospective review of 411 consecutive human immunodeficiency virus-negative patients with uveitis (571 affected eyes) and report on prevalence, risk factors and visual outcomes of patients with RRD. : Prevalence of RRD was 7% of all patients with uveitis. Multivariate analysis revealed that posterior uveitis and panuveitis were associated with RRD ( = 0.001). Strong association between RRD development and infectious uveitis was also observed ( = 0.009). Acute retinal necrosis (ARN) was firmly associated with RRD development ( = 0.016). Although anatomical success was obtained, functional outcome was poor. Poor visual outcomes at 6-month and 1-year follow-up were associated with initial VA < counting fingers ( = 0.05,  = 0.044). : Prevalence of RRD in uveitis was 7% and development of RRD was encountered in posterior and panuveitis. Infectious uveitis (specifically ARN) formed a high risk for RRD.

摘要

: 描述葡萄膜炎患者发生孔源性视网膜脱离(RRD)的风险因素。 : 我们对 411 例连续的人类免疫缺陷病毒阴性葡萄膜炎患者(571 只患眼)进行了回顾性分析,报告了 RRD 患者的患病率、风险因素和视力结果。 : RRD 的患病率占所有葡萄膜炎患者的 7%。多变量分析显示,后葡萄膜炎和全葡萄膜炎与 RRD 相关(=0.001)。还观察到 RRD 发生与感染性葡萄膜炎之间存在强烈关联(=0.009)。急性视网膜坏死(ARN)与 RRD 的发生密切相关(=0.016)。尽管获得了解剖学上的成功,但功能结果较差。6 个月和 1 年随访时视力较差与初始 VA<数指(=0.05,=0.044)有关。 : 葡萄膜炎中 RRD 的患病率为 7%,RRD 发生于后葡萄膜炎和全葡萄膜炎。感染性葡萄膜炎(特别是 ARN)是 RRD 的高危因素。

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