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基于镧系元素的纳米结构在超高场磁共振成像探针中的最新进展。

Recent Advances in Lanthanide Based Nano-Architectures as Probes for Ultra High-Field Magnetic Resonance Imaging.

机构信息

Laboratory of Bioinorganic Chemistry, Department of Chemistry, KU Leuven, Celestijnenlaan 200F, Leuven 3001, Belgium.

出版信息

Curr Med Chem. 2020;27(3):352-361. doi: 10.2174/0929867325666180201110244.

Abstract

Paramagnetic Lanthanide ions incorporated into nano- architectures are emerging as a versatile platform for Magnetic Resonance Imaging (MRI) contrast agents due to their strong contrast enhancement effects combined with the platform capability to include multiple imaging modalities. This short review examines the application of lanthanide based nanoarchitectures (nanoparticles and nano- assemblies) in the development of multifunctional probes for single and multimodal imaging involving high field MRI as one imaging modality.

摘要

镧系顺磁离子掺入纳米结构中,由于其强大的对比增强效应以及包含多种成像模式的平台能力,正成为磁共振成像(MRI)对比剂的多功能平台。这篇简短的综述检查了基于镧系的纳米结构(纳米粒子和纳米组装体)在开发用于单模态和多模态成像的多功能探针中的应用,其中高场 MRI 是一种成像模式。

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