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8岁患者伴骨质吸收的Hallopeau连续性肢端皮炎:一例报告

Acrodermatitis Continua of Hallopeau with Bone Resorption in an 8-Year-Old Patient: A Case Report.

作者信息

Alorainy May, Alshaya Mohammed, Al-Rikabi Ammar, Ayesh Mohammed, Alsaif Fahad

机构信息

College of Medicine, King Saud University, Riyadh, Saudi Arabia.

Saudi Commission for Health Specialties, Riyadh, Saudi Arabia.

出版信息

Case Rep Dermatol. 2017 Dec 18;9(3):259-264. doi: 10.1159/000485370. eCollection 2017 Sep-Dec.

DOI:10.1159/000485370
PMID:29422844
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5803711/
Abstract

Acrodermatitis continua of Hallopeau (ACH) is an uncommon inflammatory disease manifesting as sterile pustular eruption of the fingers and toes. The disease is of a chronic relapsing nature and is often refractory to treatment. With longstanding disease, osteitis with consequent bone resorption of the underlying phalanges can occur, leading to disability. While the incidence of ACH is rare in children, complications like osteolysis have not been reported previously in this age group. In this paper, we report the case of an 8-year-old boy with severe ACH complicated by bone resorption.

摘要

哈洛佩奥连续性肢端皮炎(ACH)是一种罕见的炎症性疾病,表现为手指和脚趾的无菌性脓疱疹。该疾病具有慢性复发性,且常常难以治疗。随着病情长期发展,可发生骨质炎,进而导致其下方指骨的骨质吸收,最终导致残疾。虽然ACH在儿童中的发病率很低,但此前尚未有该年龄组发生骨质溶解等并发症的报道。在本文中,我们报告了一例患有严重ACH并伴有骨质吸收的8岁男孩的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4ff/5803711/af0dd1a4a5c4/cde-0009-0259-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4ff/5803711/52c1a85f5736/cde-0009-0259-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4ff/5803711/b0e65876d539/cde-0009-0259-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4ff/5803711/af0dd1a4a5c4/cde-0009-0259-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4ff/5803711/52c1a85f5736/cde-0009-0259-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4ff/5803711/b0e65876d539/cde-0009-0259-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4ff/5803711/af0dd1a4a5c4/cde-0009-0259-g03.jpg

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本文引用的文献

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Acrodermatitis Continua of Hallopeau with Granuloma-like Vegetation, Osteolysis and IL36RN Mutation.伴有肉芽肿样赘生物、骨质溶解和IL36RN突变的Hallopeau连续性肢端皮炎
Acta Derm Venereol. 2017 Jan 4;97(1):122-123. doi: 10.2340/00015555-2468.
2
IL36RN Mutations Affect Protein Expression and Function: A Basis for Genotype-Phenotype Correlation in Pustular Diseases.IL36RN突变影响蛋白质表达和功能:脓疱性疾病中基因型-表型相关性的基础。
J Invest Dermatol. 2016 Sep;136(9):1811-1819. doi: 10.1016/j.jid.2016.04.038. Epub 2016 May 21.
3
Pustules of the fingers: acrodermatitis continua.
手指脓疱:连续性肢端皮炎。
CMAJ. 2016 Oct 18;188(15):1105. doi: 10.1503/cmaj.150955. Epub 2016 Mar 29.
4
Acrodermatitis continua of hallopeau evolving into generalised pustular psoriasis.哈洛佩au连续性肢端皮炎演变为泛发性脓疱型银屑病。
Indian J Dermatol. 2013 Mar;58(2):161. doi: 10.4103/0019-5154.108096.
5
Acrodermatitis continua of Hallopeau is a clinical phenotype of DITRA: evidence that it is a variant of pustular psoriasis.豪尔珀特连续性肢端皮炎是 DITRA 的一种临床表型:它是脓疱型银屑病的一种变异型的证据。
Dermatology. 2013;226(1):28-31. doi: 10.1159/000346572. Epub 2013 Feb 15.
6
Acrodermatitis continua of Hallopeau: evolution of treatment options.Hallopeau 连续性肢端皮炎:治疗选择的演变。
Int J Dermatol. 2011 Oct;50(10):1195-211. doi: 10.1111/j.1365-4632.2011.04993.x.
7
Psoriasis in children: a retrospective analysis.儿童银屑病:回顾性分析。
J Eur Acad Dermatol Venereol. 2011 Apr;25(4):417-21. doi: 10.1111/j.1468-3083.2010.03801.x.
8
Successful treatment of a 9-year-old boy affected by acrodermatitis continua of Hallopeau with targeted ultraviolet B narrow-band phototherapy.成功应用靶向紫外线 B 窄谱光疗治疗一例 Hallopeau 连续性肢端皮炎患儿
Photodermatol Photoimmunol Photomed. 2010 Feb;26(1):41-3. doi: 10.1111/j.1600-0781.2009.00468.x.
9
British Association of Dermatologists' guidelines for biologic interventions for psoriasis 2009.英国皮肤科医师协会2009年银屑病生物治疗指南。
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10
An infant with acrodermatitis continua of Hallopeau: successful treatment with thalidomide and UVB therapy.一名患有哈洛佩奥连续性肢端皮炎的婴儿:沙利度胺和紫外线B光疗成功治愈
Pediatr Dermatol. 2009 Jan-Feb;26(1):105-6. doi: 10.1111/j.1525-1470.2008.00838.x.