Pediatric Dermatology Unit, Dermatology Department, University of Athens, Andreas Sygros Hospital, Athens, Greece.
J Eur Acad Dermatol Venereol. 2011 Apr;25(4):417-21. doi: 10.1111/j.1468-3083.2010.03801.x.
Few epidemiological studies are available on childhood psoriasis.
Between 2005 and 2008, information was collected about all children diagnosed with psoriasis in the Pediatric Dermatology Unit of Andreas Sygros Skin Hospital, in Athens, Greece.
A total of 125 children with psoriasis were examined, the male to female ratio was 1.4:1 and the peak age of onset was in the 9- to 10-year-old age group. Only 16% of the patients had a positive family history. Plaque type psoriasis was the most prevalent type at presentation with 56.8% of the children affected, followed by scalp involvement (33.6%). The limbs were the most prevalent site of involvement (70 children, 56%), followed by the body (59 children, 47.2%) and scalp (60 children, 48%) equally affected. Most of the children had <5% of their skin affected by psoriasis (53.2%). Age of onset had no influence on the severity of the disease (P=0.107), whereas a positive correlation was found with sex and severity of the disease, with male patients being more severely affected (P=0.008). Family history did not influence the age at presentation (P=0.68). Topical steroids were used in most commonly followed by keratolytics, calcipotriol, topical tacrolimus and topical pimecrolimus.
Our study reflects the patterns of presentation of childhood psoriasis in sunny countries like Greece.
关于儿童银屑病的流行病学研究较少。
2005 年至 2008 年期间，在希腊雅典 Andreas Sygros 皮肤医院的儿科皮肤科收集了所有被诊断为银屑病的儿童的信息。
共检查了 125 例银屑病患儿，男女比例为 1.4:1，发病高峰年龄在 9-10 岁。仅有 16%的患者有阳性家族史。斑块型银屑病是最常见的发病类型，占 56.8%，其次是头皮受累（33.6%）。受累最常见的部位是四肢（70 例，56%），其次是躯干（59 例，47.2%）和头皮（60 例，48%）。大多数患儿的皮肤受累面积<5%（53.2%）。发病年龄与疾病严重程度无影响（P=0.107），而与性别和疾病严重程度呈正相关，男性患儿的病情更严重（P=0.008）。家族史对发病年龄无影响（P=0.68）。最常用的治疗方法是外用类固醇，其次是角质松解剂、卡泊三醇、外用他克莫司和外用吡美莫司。
我们的研究反映了阳光充足的国家（如希腊）儿童银屑病的发病模式。
