Department of Nutrition & Dietetics, The Royal Hospital for Children, Glasgow, UK.
Human Nutrition, School of Medicine, College of Medicine, Veterinary and Life Sciences, New Lister Building, Glasgow Royal Infirmary, University of Glasgow, Glasgow, UK.
Acta Paediatr. 2018 Jun;107(6):1094-1099. doi: 10.1111/apa.14268. Epub 2018 Mar 8.
This paper describes the outcomes of gastrostomy feeding in patients with Crohn's disease (CD).
Patients with CD who attended the Royal Hospital for Children, Glasgow and received gastrostomy feeding for at least two years between 2003 and 2010 were identified from the clinical database. The data recorded included the anthropometric data, CD phenotype, the surgical technique that was used, complications, medication, feed type, median feed, calories, volume and clinical outcomes.
The study identified 16 patients (14 male) who had a gastrostomy inserted using a pull technique at a median age of 12.6 years. Of these two required laparoscopic placement. Short-term complications lasting less than one month were experienced by nine (56%) patients and one (6%) experienced long-term complications. Anthropometry significantly improved at follow-up compared to baseline: at 12 months, the body mass index z-score was 1.11 (p = 0.005) and the weight z-score was 0.19 (p < 0.05). At 24 months, the height z-score was -1.03 (p = 0.04). The daily median volume and calories from feeds increased significantly from baseline to post-PEG insertion, from 400 to 738 mL and 705 to 860 kcal/day (p ≤ 0.01).
Gastrostomy feeding for paediatric patients with CD was associated with improved nutrition, weight gain and growth outcomes.
本文描述了克罗恩病(CD)患者胃造口喂养的结果。
从临床数据库中确定了 2003 年至 2010 年间在格拉斯哥皇家儿童医院接受胃造口喂养至少两年的 CD 患者。记录的数据包括人体测量数据、CD 表型、使用的手术技术、并发症、药物、喂养类型、中位喂养量、热量、容量和临床结果。
研究确定了 16 名(14 名男性)患者,他们在中位数为 12.6 岁时使用拉拔技术插入了胃造口管。其中两名需要腹腔镜放置。9 名(56%)患者出现了持续时间短于一个月的短期并发症,1 名(6%)患者出现了长期并发症。与基线相比,随访时的人体测量数据明显改善:12 个月时,体重指数 z 分数为 1.11(p = 0.005),体重 z 分数为 0.19(p < 0.05)。24 个月时,身高 z 分数为-1.03(p = 0.04)。从基线到 PEG 插入后,每日中位喂养量和热量明显增加,从 400 毫升增加到 738 毫升,从 705 千卡增加到 860 千卡/天(p ≤ 0.01)。
胃造口喂养小儿 CD 患者与改善营养、体重增加和生长结果相关。