Vida Vladimiro L, Zanotto Lorenza, Carrozzini Massimiliano, Padalino Massimo A, Stellin Giovanni
Pediatric and Congenital Cardiac Surgery Unit, Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Padua, Italy.
Pediatric and Congenital Cardiac Surgery Unit, Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Padua, Italy..
Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2018 Mar;21:41-45. doi: 10.1053/j.pcsu.2017.11.004.
Congenital mitral valve (MV) dysplasia is a relatively rare and highly complex cardiac disease. We sought to provide a comprehensive analysis of the current surgical techniques for treating mitral valve insufficiency and the results of mitral valve repair at our institution. Between 1972 and 2017, 104 consecutive patients underwent surgical repair of congenital MV dysplasia-insufficiency at our institution. Among these, 59 patients presented with MV insufficiency (or prevalent MV insufficiency) and were part of the study. There was 1 early (1.7%) and 1 late death (1.7%). Survival at 5, 10 and 20 years was 98%, 98% and 94%, respectively. Eight patients (14%) required MV replacement for residual significant MV insufficiency. Freedom from re-intervention for MV dysfunction at 5, 10 and 20 years were 89%, 84% and 79%, respectively. Surgical techniques for treating mitral valve insufficiency must be tailored for each patient with the main goal of achieving a proper valve function, rather than a "normal" anatomy. The mechanism underlying valve dysfunction in congenital mitral valve insufficiency is multifactorial and requires the application of a variety of surgical techniques in each case.
先天性二尖瓣发育异常是一种相对罕见且高度复杂的心脏疾病。我们试图对当前治疗二尖瓣关闭不全的手术技术以及我院二尖瓣修复的结果进行全面分析。1972年至2017年期间,我院连续104例患者接受了先天性二尖瓣发育异常-关闭不全的手术修复。其中,59例患者存在二尖瓣关闭不全(或主要为二尖瓣关闭不全)并纳入研究。有1例早期死亡(1.7%)和1例晚期死亡(1.7%)。5年、10年和20年的生存率分别为98%、98%和94%。8例患者(14%)因二尖瓣残留严重关闭不全而需要进行二尖瓣置换。5年、10年和20年无二尖瓣功能障碍再次干预的比例分别为89%、84%和79%。治疗二尖瓣关闭不全的手术技术必须针对每位患者进行调整,主要目标是实现适当的瓣膜功能,而非“正常”解剖结构。先天性二尖瓣关闭不全中瓣膜功能障碍的机制是多因素的,每种情况都需要应用多种手术技术。