Division of Trauma and Emergency Surgery, Chang Gung Memorial Hospital, 5 Fu-Xing Street, Guishan District, Taoyuan City, Taiwan, Republic of China.
Eur J Trauma Emerg Surg. 2019 Jun;45(3):455-460. doi: 10.1007/s00068-018-0917-8. Epub 2018 Feb 9.
This study aimed to clarify the prognosis of polytrauma patients presenting to the emergency department (ED) with a Glasgow Coma Scale score (GCS) of 3.
A trauma registry system has been established at our institution since 2009. The current study reviewed patients in the registry who presented to the ED with a GCS of 3 from January 2011 to December 2015. Surviving and non-surviving patients were compared to identify the prognostic factors of patient survival. The study also aimed to determine the factors contributing to patients who survived with a GCS > 13 at discharge.
During the study period, 145 patients were enrolled in the study, 119 of whom (82.1%) did not survive the traumatic insult. Of the 26 survivors, 13 (9.0%) had a GCS of 14 or 15 at discharge. The multiple logistic regression revealed that a lack of bilateral dilated and fixed pupils (BFDP) (OR 5.967, 95% CI 1.780-19.997, p = 0.004) and a GCS > 3 after resuscitation (OR 6.875, 95% CI 2.135-22.138, p = 0.001) were independent prognostic factors of survival. Based on the multiple logistic regression, an age under 40 years (OR 16.405, 95% CI 1.520-177.066, p = 0.021) and a GCS > 3 after resuscitation (OR 12.100, 95% CI 1.058-138.352, p = 0.045) were independent prognostic factors of a GCS > 13 at discharge.
Aggressive resuscitation still provided benefit to polytrauma patients presenting with a GCS of 3, especially those with a rapid response to the resuscitation. Young patients with a deep coma on arrival had a higher probability of functional recovery after resuscitation in the ED.
本研究旨在阐明格拉斯哥昏迷评分(GCS)为 3 分的创伤患者在急诊科(ED)就诊的预后。
自 2009 年以来,我们机构建立了创伤登记系统。本研究回顾了 2011 年 1 月至 2015 年 12 月期间在 ED 就诊 GCS 为 3 分的登记患者。将存活患者与死亡患者进行比较,以确定患者生存的预后因素。本研究还旨在确定导致出院时 GCS>13 分的存活患者的因素。
在研究期间,共有 145 名患者入组研究,其中 119 名(82.1%)未从创伤中存活。26 名幸存者中,有 13 名(9.0%)出院时 GCS 为 14 或 15 分。多因素逻辑回归显示,双侧瞳孔散大固定(BFDP)缺失(OR 5.967,95%CI 1.780-19.997,p=0.004)和复苏后 GCS>3(OR 6.875,95%CI 2.135-22.138,p=0.001)是生存的独立预后因素。基于多因素逻辑回归,年龄<40 岁(OR 16.405,95%CI 1.520-177.066,p=0.021)和复苏后 GCS>3(OR 12.100,95%CI 1.058-138.352,p=0.045)是出院时 GCS>13 分的独立预后因素。
积极的复苏治疗仍然对 GCS 为 3 分的创伤患者有益,尤其是对复苏反应迅速的患者。到达时深昏迷的年轻患者在 ED 复苏后更有可能恢复功能。