Department of Emergency Medicine, San Antonio Military Medical Center, 3841 Roger Brooke Dr, Fort Sam Houston, TX, 78234, USA.
Department of Emergency Medicine, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX, 75390, USA.
Intern Emerg Med. 2018 Apr;13(3):375-383. doi: 10.1007/s11739-018-1799-9. Epub 2018 Feb 9.
Toxic alcohols are a group of substances containing a hydroxyl group not meant to be ingested. They are the cause of a significant number of accidental and non-accidental exposures. Toxic alcohol poisoning can be associated with a significant degree of morbidity and mortality if not promptly recognized and treated. This review describes the clinical presentation and an approach to the recognition and management for toxic alcohol poisoning. Toxic alcohols classically refer to a group of alcohols not meant for ingestion. Methanol, ethylene glycol, and isopropyl alcohol are readily available in common hardware and household materials. Toxic alcohols are ingested for a variety of reasons including accidental exposures, intentional inebriation, homicide and suicide. The patient with an altered mental status or concerning history warrants consideration of this potentially deadly ingestion. Treatment considerations include alcohol dehydrogenase blockade and hemodialysis. Toxic alcohol poisoning can be an elusive diagnosis. This review evaluates toxic alcohol poisoning signs and symptoms and an approach to diagnosis and management.
有毒醇类是一组含有羟基的物质,不能被摄入。它们是导致大量意外和非意外暴露的原因。如果不能及时发现和治疗,有毒醇类中毒可能会导致严重的发病率和死亡率。本文综述了有毒醇类中毒的临床表现以及识别和治疗方法。有毒醇类通常是指一组不能摄入的醇类。甲醇、乙二醇和异丙醇在常见的五金和家用材料中很容易获得。有毒醇类被摄入的原因有很多,包括意外暴露、故意醉酒、杀人或自杀。对于出现精神状态改变或可疑病史的患者,应考虑这种潜在致命性摄入的可能性。治疗考虑包括乙醇脱氢酶阻断和血液透析。有毒醇类中毒的诊断可能很棘手。本文评价了有毒醇类中毒的体征和症状以及诊断和治疗方法。