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数字减影血管造影和经导管动脉栓塞术治疗胰切除术后出血的诊断和治疗效果:单中心回顾性队列研究。

Diagnosis and treatment efficacy of digital subtraction angiography and transcatheter arterial embolization in post-pancreatectomy hemorrhage: A single center retrospective cohort study.

机构信息

Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China.

Department of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China.

出版信息

Int J Surg. 2018 Mar;51:223-228. doi: 10.1016/j.ijsu.2018.01.045. Epub 2018 Feb 8.

DOI:10.1016/j.ijsu.2018.01.045
PMID:29427752
Abstract

BACKGROUND

To evaluate the diagnostic and treatment efficacy of digital subtraction angiography (DSA), transcatheter arterial embolization (TAE) in post-pancreatectomy hemorrhage (PPH).

MATERIALS AND METHODS

This is a single-center retrospective cohort study. Clinicopathological data of 23 patients with PPH from August 2009 to November 2016 were collected. We observed (1) DSA procedures and hemorrhagic sites (2) TAE: successful rate and complications (3) Follow-up.

RESULTS

(1) 30 procedures of DSA were conducted in 23 patients, 20 (66.7%) procedures of contrast medium extravasation were observed. Among 20 procedures of positive DSA, hemorrhagic site located 5 times in gastroduodenal artery,4 times in common hepatic artery, 3 times in superior mesenteric artery, 3 times in splenic artery, 1 time in left gastric artery, right gastric artery, left hepatic artery, right hepatic artery and inferior mesenteric artery respectively. (2) Besides 4 failure procedures of TAE managed by surgery, 16 procedures of TAE were conducted, with 14 successful hemostasis. 2 procedures of post-TAE re-hemorrhage were managed by surgery. In 9 patients with 10 procedures of negative DSA, 9 had conservative treatment and 1 was managed by surgery. (3) 6 patients died because of the metastasis, median survival time was 7.5 months.

CONCLUSIONS

DSA is minimal invasive in the diagnosis of PPH, and TAE is safe and effective for patients with positive DSA.

摘要

背景

评估数字减影血管造影(DSA)、经导管动脉栓塞(TAE)在胰腺切除术后出血(PPH)中的诊断和治疗效果。

材料与方法

这是一项单中心回顾性队列研究。收集了 2009 年 8 月至 2016 年 11 月 23 例 PPH 患者的临床病理资料。观察(1)DSA 操作和出血部位(2)TAE:成功率和并发症(3)随访。

结果

(1)23 例患者共进行了 30 次 DSA 检查,20 次(66.7%)观察到造影剂外渗。在 20 次阳性 DSA 检查中,出血部位分别位于胃十二指肠动脉 5 次、肝总动脉 4 次、肠系膜上动脉 3 次、脾动脉 3 次、胃左动脉 1 次、胃右动脉、肝左动脉、肝右动脉和肠系膜下动脉各 1 次。(2)除 4 次 TAE 失败行手术治疗外,还进行了 16 次 TAE 治疗,14 次成功止血。2 例 TAE 后再出血患者行手术治疗。在 10 次阴性 DSA 的 9 例患者中,9 例患者行保守治疗,1 例患者行手术治疗。(3)6 例患者因转移死亡,中位生存时间为 7.5 个月。

结论

DSA 对 PPH 的诊断具有微创性,TAE 对阳性 DSA 患者安全有效。

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