Zhang Yi-Ru, Li Zhao-Yang, Liang Jing, Bai Song, Zhang Zhu-Fen
Yi-ru Zhang, Department of Emergency, Baoding No.1 Central Hospital, Baoding 071000, Hebei, China.
Zhao-yang Li, Department of Specialty Nursing, Baoding No.1 Central Hospital, Baoding 071000, Hebei, China.
Pak J Med Sci. 2023 Sep-Oct;39(5):1321-1325. doi: 10.12669/pjms.39.5.6719.
To investigate the value of mesenteric CTA combined with D-dimer (DD) level and inflammatory factor changes in evaluating the severity of mesenteric artery embolism.
This is a retrospective study. The imaging data of mesenteric CTA and the levels of plasma DD and inflammatory factors in 120 patients with mesenteric artery embolism confirmed by DSA or surgery in Baoding No.1 Central Hospital were analyzed retrospectively from January 2021 to December 2022. The coincidence rate of CTA alone and CTA combined with DD and inflammatory factors with the results of surgery or DSA was compared and analyzed. The specificity, sensitivity and accuracy of CTA alone and CTA combined with DD and inflammatory factors in diagnosing superior mesenteric artery embolism were compared. The correlations of different severity of mesenteric artery embolism with DD and inflammatory factor levels were compared and analyzed.
There was a significant difference in the coincidence rate between CTA diagnosis and CTA combined with DD and inflammatory factors diagnosis ( 0.01). And the sensitivity and accuracy of the latter were significantly higher than those of the former (sensitivity, 0.01; accuracy, 0.00). The levels of plasma DD, TNF-a, CRP and IL-6 in the intestinal wall thinning group were significantly higher than those in the thickening group ( 0.00). The above indexes increased significantly in the decreased intestinal wall enhancement group compared with the increased intestinal wall enhancement group ( 0.00). DD, TNF-ɑ, CRP and IL-6 levels increased with the increase in stenosis severity.
Mesenteric CTA combined with plasma DD and inflammatory factor levels can effectively determine the severity of mesenteric arterial embolism, and provide a scientific basis for early clinical diagnosis and treatment.
探讨肠系膜CT血管造影（CTA）联合D-二聚体（DD）水平及炎症因子变化在评估肠系膜动脉栓塞严重程度中的价值。
本研究为回顾性研究。回顾性分析2021年1月至2022年12月在保定市第一中心医院经数字减影血管造影（DSA）或手术确诊的120例肠系膜动脉栓塞患者的肠系膜CTA影像资料、血浆DD及炎症因子水平。比较分析单纯CTA以及CTA联合DD和炎症因子与手术或DSA结果的符合率。比较单纯CTA以及CTA联合DD和炎症因子诊断肠系膜上动脉栓塞的特异性、敏感性和准确性。比较分析不同严重程度肠系膜动脉栓塞与DD和炎症因子水平的相关性。
CTA诊断与CTA联合DD和炎症因子诊断的符合率有显著差异（P<0.01）。后者的敏感性和准确性显著高于前者（敏感性，P<0.01；准确性，P<0.00）。肠壁变薄组血浆DD、肿瘤坏死因子-α（TNF-α）、C反应蛋白（CRP）和白细胞介素-6（IL-6）水平显著高于肠壁增厚组（P<0.00）。肠壁强化降低组上述指标较肠壁强化增加组显著升高（P<0.
