Ezzeddine Fatima M, Dandamudi Gopi
Indiana University School of Medicine, 1801 North Senate Boulevard, Suite 4000, Indianapolis, IN 46032, USA.
Indiana University School of Medicine, 1801 North Senate Boulevard, Suite 4000, Indianapolis, IN 46032, USA.
Card Electrophysiol Clin. 2018 Mar;10(1):87-98. doi: 10.1016/j.ccep.2017.11.009.
Long-term right ventricular apical pacing has been associated with detrimental effects, including an increased risk for heart failure, atrial fibrillation, and death. Most of these adverse effects result from ventricular dyssynchrony related to perturbed ventricular depolarization. In addition, biventricular pacing has limited benefits in patients with non-left bundle branch block and severely reduced ejection fraction. Consequently, alternative pacing strategies that mimic natural physiology are desired. Recently, permanent His bundle pacing has emerged as a true physiologic form of ventricular pacing that has been shown to be safe and feasible in clinical practice.
长期右心室心尖部起搏已被证实存在有害影响，包括心力衰竭、心房颤动和死亡风险增加。这些不良反应大多源于与心室去极化紊乱相关的心室不同步。此外，双心室起搏对非左束支传导阻滞且射血分数严重降低的患者益处有限。因此，需要能够模拟自然生理状态的替代起搏策略。最近，永久性希氏束起搏已成为一种真正生理性的心室起搏方式，在临床实践中已被证明是安全可行的。
