Department of Psychiatry, University of Campania "Luigi Vanvitelli", Naples, Italy; Section of Eating Disorders, Department of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Section of Eating Disorders, Department of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Neurosci Biobehav Rev. 2018 Apr;87:133-150. doi: 10.1016/j.neubiorev.2018.02.002. Epub 2018 Feb 8.
Reactivity to interpersonal stress in patients with eating disorders: A systematic review and meta-analysis of studies using an experimental paradigm. NEUROSCI BIOBEHAV REV XXX-XXX, 2018.- Social difficulties have been implicated in the development and maintenance of eating disorder symptoms. The aim of this work was to conduct a systematic review and meta-analysis of experimental studies testing patientsö reactivity to interpersonal stress, compared to healthy controls. Thirty-four studies were included. Meta-analyses were conducted on 16 studies and on following outcomes: attention bias and interference to threatening faces, cortisol, heart rate and negative affect before and after exposure to interpersonal stress. Patients showed heightened attention bias and interference to threatening faces. Lower heart rate after exposure to interpersonal stress and greater negative affect before and after interpersonal stress were observed in the clinical group compared to controls. Surprisingly, only a small minority of studies included measures of abnormal eating behaviour and attitudes. This seems a missed opportunity for testing the causal and maintaining role that abnormalities in interpersonal stress response play in eating disorders. Nonetheless, findings corroborate the hypothesis that patients' response to interpersonal stress differs from that of healthy controls.
使用实验范式的研究的系统评价和荟萃分析。神经科学与生物行为评论，2018 年。社交困难与进食障碍症状的发展和维持有关。本研究的目的是对比较健康对照组的患者对人际压力的反应的实验研究进行系统评价和荟萃分析。共纳入 34 项研究。对 16 项研究和以下结果进行了荟萃分析：对威胁面孔的注意偏向和干扰、皮质醇、心率和暴露于人际压力前后的负面情绪。与对照组相比，患者对威胁面孔的注意力偏向和干扰更大。在临床组中，暴露于人际压力后心率较低，人际压力前后的负面情绪更大。令人惊讶的是，只有少数研究包括异常进食行为和态度的测量。这似乎是一个错失的机会，无法测试人际压力反应异常在进食障碍中的因果和维持作用。尽管如此，研究结果证实了这样一种假设，即患者对人际压力的反应不同于健康对照组。
