Neurobiology Research Unit, Rigshospitalet, 9 Blegdamsvej, 2100 Copenhagen, Denmark; Center for Integrated Molecular Brain Imaging, the Neuroscience Centre, Rigshospitalet, Copenhagen, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, 3B Blegdamsvej, 2200 Copenhagen, Denmark.
Neurobiology Research Unit, Rigshospitalet, 9 Blegdamsvej, 2100 Copenhagen, Denmark; Center for Integrated Molecular Brain Imaging, the Neuroscience Centre, Rigshospitalet, Copenhagen, Denmark.
Psychiatry Res. 2018 Apr;262:108-114. doi: 10.1016/j.psychres.2018.02.015. Epub 2018 Feb 6.
The personality traits Neuroticism and Extraversion may be involved in the development of seasonal affective disorder (SAD). However, the impact of personality traits on SAD severity and whether such self-reported traits fluctuate with season is unknown. We investigated the association between Neuroticism, as acquired in a symptom-free phase and depression severity in individuals with SAD and seasonal changes in personality traits in individuals with SAD compared to healthy controls. Twenty-nine individuals diagnosed with SAD and thirty demographically matched controls completed the NEO Personality Inventory-Revised and the Major Depression Inventory twice: in summer when individuals with SAD were symptom-free, and in winter when they experienced SAD symptoms. In summer, the groups scored similarly on their personality traits, and the controls did not score any different in winter compared to summer. High scores on Neuroticism in summer was associated with more severe depressive symptoms in winter in SAD individuals. In winter, individuals with SAD scored higher on Neuroticism and lower on Extraversion, both compared to controls and to their own summer scores. Our results support that Neuroticism may represent a vulnerability marker related to SAD, and during a depressive episode Neuroticism and Extraversion may be sensitive markers of SAD pathology.
神经质和外向性等人格特质可能与季节性情感障碍（SAD）的发展有关。然而，人格特质对 SAD 严重程度的影响，以及这些自我报告的特质是否随季节波动尚不清楚。我们研究了在 SAD 患者无症状期获得的神经质与 SAD 患者抑郁严重程度之间的关系，以及与健康对照组相比，SAD 患者的人格特质随季节的变化。29 名被诊断为 SAD 的患者和 30 名在人口统计学上相匹配的对照组完成了 NEO 人格量表修订版和 Major Depression Inventory 两次评估：一次是在 SAD 患者无症状的夏季，一次是在他们出现 SAD 症状的冬季。在夏季，两组在人格特质方面得分相似，对照组在冬季的得分与夏季没有差异。夏季神经质得分高与 SAD 患者冬季抑郁症状加重有关。在冬季，与对照组和自身夏季得分相比，SAD 患者的神经质得分更高，外向性得分更低。我们的结果支持神经质可能代表与 SAD 相关的易感性标志物，并且在抑郁发作期间，神经质和外向性可能是 SAD 病理的敏感标志物。
