Rivas Eric, Herndon David N, Chapa Martha L, Cambiaso-Daniel Janos, Rontoyanni Victoria G, Gutierrez Ileana L, Sanchez Kevin, Glover Shauna, Suman Oscar E
Shriners Hospitals for Children, Galveston, TX, USA; Department of Surgery, University of Texas Medical Branch, Galveston, TX, USA; Department of Kinesiology & Sport Management, Texas Tech University, Lubbock, TX, USA.
Shriners Hospitals for Children, Galveston, TX, USA; Department of Surgery, University of Texas Medical Branch, Galveston, TX, USA.
Burns. 2018 Aug;44(5):1187-1194. doi: 10.1016/j.burns.2018.01.014. Epub 2018 Feb 9.
Females have a 50% increased risk of death from burn injury compared to males. However, whether exercise capacity and exercise induced training adaptations differ between burned boys and girls is unknown. This project tested the hypothesis that girls with burns have lower exercise capacity and different exercise induced training adaptations.
Twenty-five girls were matched to 26 boys (mean, 95%CI; years 13 [12,14], cm 151 [143,161], kg 54 [45,63]; each P>0.05) for burn injury (% total body surface area burn, 54 [45,62]; P=0.82). Lean body mass (LBM), strength (peak torque) and cardiorespiratory fitness (peak VO) were normalized to kg LBM and compared as a percentage of age-sex matched non-burned children (n=26 boys, years 13 [12,14]; n=25 girls, years 13 [12,14]) at discharge (DC) and after aerobic and resistance rehabilitation exercise training (RET).
Using a 2-way factorial ANOVA (group×time), we found both groups had similar 11% change in LBM (87.3% of non-burned values [82.2,92.3]) and after the RET (92.8% [87.2,98.3]; main effect, time P<0.0001). Peak torque increased similarly by 16% in both groups (% of age-sex matched non-burned DC, 55.9 [51.3,60.5]; after RET, 77.5 [72.1,82.9]; main effect, time P<0.0001). Likewise, peak VO increased in both groups by 15% (% of age-sex matched non-burned DC, 56.8 [52.4,61.2] to RET, 72.2 [67.6,76.8]; main effect, time; P<0.0001). Burned children exercise at greater percentage of their peak VO and peak HR compared to non-burned children (Interaction, group×time, P<0.0001).
The burn injury does not have sex-dependent effects on LBM or exercise capacity in severely burn injured children. Differences in relative peak VO and peak HR suggest the need for burn specific exercise programs for improving the efficacy of a rehabilitation program.
与男性相比，女性因烧伤死亡的风险增加50%。然而，烧伤男孩和女孩的运动能力以及运动诱导的训练适应性是否存在差异尚不清楚。本项目检验了以下假设：烧伤女孩的运动能力较低，且运动诱导的训练适应性不同。
25名女孩与26名男孩（平均年龄，95%置信区间；13岁[12,14岁]，身高151厘米[143,161厘米]，体重54千克[45,63千克]；每组P>0.05）烧伤情况相匹配（烧伤占体表面积的百分比，54%[45,62%]；P=0.82）。瘦体重（LBM）、力量（峰值扭矩）和心肺适能（峰值摄氧量）以每千克瘦体重进行标准化，并与出院时（DC）以及有氧和抗阻康复运动训练（RET）后的年龄和性别匹配的未烧伤儿童（n=26名男孩，13岁[12,14岁]；n=25名女孩，13岁[12,14岁]）的相应指标进行比较，以百分比表示。
使用双因素方差分析（组×时间），我们发现两组的瘦体重变化相似，均为11%（为未烧伤值的87.3%[82.2,92.3]），RET后为92.8%[87.2,98.3]；主效应，时间P<0.0001）。两组的峰值扭矩同样增加了16%（年龄和性别匹配的未烧伤DC组的百分比，55.9[51.3,60.5]；RET后，77.5[72.1,82.9]；主效应，时间P<0.0001）。同样，两组的峰值摄氧量均增加了15%（年龄和性别匹配的未烧伤DC组的百分比，56.8[52.4,61.2]至RET后，72.2[67.6,76.8]；主效应，时间；P<0.0001）。与未烧伤儿童相比，烧伤儿童在其峰值摄氧量和峰值心率的更大百分比下进行运动（交互作用，组×时间，P<0.0001）。
烧伤对严重烧伤儿童的瘦体重或运动能力没有性别依赖性影响。相对峰值摄氧量和峰值心率的差异表明，需要针对烧伤制定特定的运动计划，以提高康复计划的效果。
