视神经鞘膜瘤早期采用分次立体定向放射治疗后视力迅速恢复。
Rapid recovery of vision following early intervention with fractionated stereotactic radiotherapy for optic nerve sheath meningioma.
作者信息
Inoue Toshihiko, Okuno Yoshishige, Nishiguchi Iku, Ikenaga Koji, Mimura Osamu
机构信息
Department of Radiation Oncology, Ashiya Radiotherapy Clinic Nozomi, Ashiya, Japan.
Department of Neuro-Ophthalmological Therapeutics, Hyogo College of Medicine, Nishinomiya, Japan.
出版信息
Int Med Case Rep J. 2018 Jan 30;11:17-22. doi: 10.2147/IMCRJ.S149592. eCollection 2018.
PURPOSE
To report the outcomes of early intervention with fractionated stereotactic radiotherapy (FSRT) in a patient with primary optic nerve sheath meningioma (ONSM).
PATIENT AND METHODS
A male patient in his early 40s underwent 5-beam FSRT at a prescribed dose of 50 Gy in 25 fractions over 35 days. The patient had an 11-month history of progressive visual impairment at the time of FSRT.
RESULTS
On day 14 of treatment, the patient reported early improvement in his vision. Two weeks after the completion of FSRT, his left eye visual acuity and field recovered completely. However, the tumor regressed only slightly in the 2 years of follow-up.
CONCLUSION
Early intervention with FSRT for optic nerve sheath meningioma resulted in a rapid response and complete improvement of visual impairment.
目的
报告原发性视神经鞘膜瘤（ONSM）患者接受分次立体定向放射治疗（FSRT）早期干预的结果。
患者与方法
一名40岁出头的男性患者接受了5野FSRT，规定剂量为50 Gy，分25次，在35天内完成。该患者在接受FSRT时已有11个月的进行性视力损害病史。
结果
在治疗第14天，患者报告视力早期改善。FSRT完成后两周，他的左眼视力和视野完全恢复。然而，在2年的随访中肿瘤仅略有退缩。
结论
对视神经鞘膜瘤进行FSRT早期干预可导致快速反应并使视力损害完全改善。
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